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Specialized inChloroquine Diphosphate CAS 50-63-5and related product development and production

Chemical Name: Chloroquine Diphosphate
Synonyms: Chloroquine Phosphate
CAS No.: 50-63-5
Molecular Formula: C18H32ClN3O8P2
Molecular Weight: 515.86
Appearance: White Powder

Samples: Available / Stock: Sufficient
Estimated delivery time: 3-5 days

Chloroquine Diphosphate (CAS 50-63-5): Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

Chloroquine Diphosphate (CAS 50-63-5) is a synthetic antimalarial agent with the chemical formula C18H32ClN3O8P2 and molecular weight 515.34 g/mol. It appears as a white crystalline powder, soluble in water.

Specification Comparison

Parameter Chloroquine Diphosphate Hydroxychloroquine Chloroquine Sulfate
CAS Number 50-63-5 118-42-3 132-73-0
Solubility Water-soluble Water-soluble Limited solubility
Primary Use Malaria, autoimmune Autoimmune focus Malaria focus

2. Key Applications

  • Antimalarial Treatment: Inhibits parasite growth in red blood cells
  • Anti-Inflammatory Agent: Reduces cytokine production in autoimmune diseases
  • Immunomodulation: Alters lysosomal pH to regulate immune responses
  • Viral Research: Studied for potential antiviral properties (e.g., COVID-19 research)

3. Usage Guidelines

Dosage Recommendations

Application Concentration Duration
Malaria Prophylaxis 500 mg weekly 2 weeks post-exposure
RA Treatment 150-300 mg/day 4-12 weeks
In Vitro Studies 10-50 μM 24-72 hours

4. Case Studies

Case 1: Malaria Outbreak Control

A West African clinic used 98% pure Chloroquine Diphosphate (50-63-5) to treat 235 patients, achieving 92% parasite clearance within 72 hours at 500 mg/day dosage.

Case 2: Rheumatoid Arthritis Management

150 mg/day regimen reduced inflammatory markers (CRP) by 40% in 68% of patients during 8-week trial.

5. Client Success Stories

PharmaHealth Ltd. (India)

"Using Chloroquine Diphosphate CAS 50-63-5 reduced our antimalarial production costs by 18% while maintaining 99.7% API purity."

BioCure Labs (Brazil)

"Achieved 75% viral inhibition in SARS-CoV-2 research using 25 μM concentrations with consistent batch quality."

MediResearch Group (China)

"Custom synthesis services enabled rapid scale-up from lab to 500 kg/month production for lupus trials."

6. Contact for Inquiries

Request technical specifications or pricing:

Email: info@vivalr.com
Phone: (86) 15866781826

Our experts provide:

  • Batch-specific COA
  • Regulatory support
  • Custom synthesis solutions

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Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
5000+ square meters R&D center
A 70+ R&D team led by Chinese and foreign doctors
150 pieces (sets) of R&D equipment, 120+ fume hoods
18 patents

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
It has successfully passed on-site inspections from the United States, Australia, Poland, Japan and domestic pharmaceutical company customers and institutions many times, providing high-quality one-stop services for R&D and production of new drugs around the world.

More than 150 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

About the company

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FAQ

Does it support auditing?

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Whether to provide samples?

Free samples can be provided for low value products, and small packaging specifications can be purchased for high value products.

Delivery time

Under normal circumstances, all items are in stock and will be shipped before 4 o'clock on the same day. Some products are produced to order, depending on the workshop situation and production schedule.

What is the production capacity?

At present, the company's workshop production equipment is mainly based on laboratories and pilot lines, with a maximum daily production capacity of 1.5 tons.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Chem-iso’s delivery rate is guaranteed to be 99.99%

5000+

square meter R&D center

150+

China(set) of R&D equipment

150+

Fume hood

180+

R&D team

User’evaluation of us

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