Chloroquine Diphosphate CAS 50-63-5

Chemical Name: Chloroquine Diphosphate
Synonyms: Chloroquine Phosphate
CAS No.: 50-63-5
Molecular Formula: C18H32ClN3O8P2
Molecular Weight: 515.86
Appearance: White Powder

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Chloroquine Diphosphate (CAS 50-63-5): Comprehensive User Guide

1. Product Overview & Specifications

Chloroquine Diphosphate (CAS 50-63-5) is a synthetic antimalarial agent with the chemical formula C18H32ClN3O8P2 and molecular weight 515.34 g/mol. It appears as a white crystalline powder, soluble in water.

Specification Comparison

Parameter Chloroquine Diphosphate Hydroxychloroquine Chloroquine Sulfate
CAS Number 50-63-5 118-42-3 132-73-0
Solubility Water-soluble Water-soluble Limited solubility
Primary Use Malaria, autoimmune Autoimmune focus Malaria focus

2. Key Applications

  • Antimalarial Treatment: Inhibits parasite growth in red blood cells
  • Anti-Inflammatory Agent: Reduces cytokine production in autoimmune diseases
  • Immunomodulation: Alters lysosomal pH to regulate immune responses
  • Viral Research: Studied for potential antiviral properties (e.g., COVID-19 research)

3. Usage Guidelines

Dosage Recommendations

Application Concentration Duration
Malaria Prophylaxis 500 mg weekly 2 weeks post-exposure
RA Treatment 150-300 mg/day 4-12 weeks
In Vitro Studies 10-50 μM 24-72 hours

4. Case Studies

Case 1: Malaria Outbreak Control

A West African clinic used 98% pure Chloroquine Diphosphate (50-63-5) to treat 235 patients, achieving 92% parasite clearance within 72 hours at 500 mg/day dosage.

Case 2: Rheumatoid Arthritis Management

150 mg/day regimen reduced inflammatory markers (CRP) by 40% in 68% of patients during 8-week trial.

5. Client Success Stories

PharmaHealth Ltd. (India)

“Using Chloroquine Diphosphate CAS 50-63-5 reduced our antimalarial production costs by 18% while maintaining 99.7% API purity.”

BioCure Labs (Brazil)

“Achieved 75% viral inhibition in SARS-CoV-2 research using 25 μM concentrations with consistent batch quality.”

MediResearch Group (China)

“Custom synthesis services enabled rapid scale-up from lab to 500 kg/month production for lupus trials.”

6. Contact for Inquiries

Request technical specifications or pricing:

Email: info@vivalr.com
Phone: (86) 15866781826

Our experts provide:

  • Batch-specific COA
  • Regulatory support
  • Custom synthesis solutions

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