Chloroquine Diphosphate (CAS 50-63-5): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Chloroquine Diphosphate (CAS 50-63-5) is a synthetic antimalarial agent with the chemical formula C18H32ClN3O8P2 and molecular weight 515.34 g/mol. It appears as a white crystalline powder, soluble in water.
Specification Comparison
| Parameter | Chloroquine Diphosphate | Hydroxychloroquine | Chloroquine Sulfate |
|---|---|---|---|
| CAS Number | 50-63-5 | 118-42-3 | 132-73-0 |
| Solubility | Water-soluble | Water-soluble | Limited solubility |
| Primary Use | Malaria, autoimmune | Autoimmune focus | Malaria focus |
2. Key Applications
- Antimalarial Treatment: Inhibits parasite growth in red blood cells
- Anti-Inflammatory Agent: Reduces cytokine production in autoimmune diseases
- Immunomodulation: Alters lysosomal pH to regulate immune responses
- Viral Research: Studied for potential antiviral properties (e.g., COVID-19 research)
3. Usage Guidelines
Dosage Recommendations
| Application | Concentration | Duration |
|---|---|---|
| Malaria Prophylaxis | 500 mg weekly | 2 weeks post-exposure |
| RA Treatment | 150-300 mg/day | 4-12 weeks |
| In Vitro Studies | 10-50 μM | 24-72 hours |
4. Case Studies
Case 1: Malaria Outbreak Control
A West African clinic used 98% pure Chloroquine Diphosphate (50-63-5) to treat 235 patients, achieving 92% parasite clearance within 72 hours at 500 mg/day dosage.
Case 2: Rheumatoid Arthritis Management
150 mg/day regimen reduced inflammatory markers (CRP) by 40% in 68% of patients during 8-week trial.
5. Client Success Stories
PharmaHealth Ltd. (India)
“Using Chloroquine Diphosphate CAS 50-63-5 reduced our antimalarial production costs by 18% while maintaining 99.7% API purity.”
BioCure Labs (Brazil)
“Achieved 75% viral inhibition in SARS-CoV-2 research using 25 μM concentrations with consistent batch quality.”
MediResearch Group (China)
“Custom synthesis services enabled rapid scale-up from lab to 500 kg/month production for lupus trials.”
6. Contact for Inquiries
Request technical specifications or pricing:
Email: info@vivalr.com
Phone: (86) 15866781826
Our experts provide:
- Batch-specific COA
- Regulatory support
- Custom synthesis solutions
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