Diethyl 1,3-Acetonedicarboxylate (CAS 105-50-0) Comprehensive Guide 2025
Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industrial Uses
- 3. Performance Comparison with Similar Esters
- 4. Usage Scenarios & Best Practices
- 5. Verified Customer Case Studies
- 6. Technical Support & Inquiry
1. Product Overview & Specifications
| Parameter | Diethyl 1,3-Acetonedicarboxylate | Typical Esters |
|---|---|---|
| CAS Number | 105-50-0 | Varies |
| Molecular Formula | C8H12O5 | Depends on structure |
| Purity Grade | >99% (Pharma Grade Available) | 70-98% |
| Boiling Point | 280-282°C | 150-250°C |
| Solubility | Soluble in Organic Solvents | Variable |
2. Key Applications & Industrial Uses
Primary Functions:
- Pharmaceutical Intermediate: Used in synthesis of antihypertensive drugs and CNS agents
- Organic Synthesis: Building block for heterocyclic compounds (pyrazoles, pyrimidines)
- Polymer Chemistry: Monomer for specialty polyesters
- Agrochemicals: Precursor for crop protection agents
3. Performance Comparison with Similar Esters
| Feature | Diethyl 1,3-Acetonedicarboxylate | Dimethyl Analog | Dipropyl Variant |
|---|---|---|---|
| Reactivity | High | Moderate | Low |
| Thermal Stability | Excellent | Good | Fair |
| Pharma Compatibility | USP/EP Certified | Industrial Grade | Limited |
4. Usage Scenarios & Best Practices
Typical Reaction Protocol:
- Use under inert atmosphere (N2 or Ar)
- Optimal reaction temperature: 60-80°C
- Recommended solvent: Anhydrous THF or DMF
- Stoichiometric ratio: 1:1.2 with amine derivatives
5. Verified Customer Case Studies
Case 1: Pharmaceutical Intermediate Production
Client: EuroPharma Solutions (Germany)
- Application: Synthesis of valsartan intermediate
- Result: 22% yield improvement vs previous synthesis route
- Purity Achieved: 99.8% (HPLC)
Case 2: Agrochemical Development
Client: AgroChem Co., Ltd (Japan)
- Application: Fungicide precursor synthesis
- Outcome: 40% cost reduction in key reaction step
- Scale: 5 metric tons/month production
6. Technical Support & Inquiry
For technical specifications sheets or bulk pricing:
- Email: info@vivalr.com
- Tel: (86) 15866781826
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