6-Chlorohexanol Cas 2009-83-8

Chemical Name: 6-Chlorohexanol
Other Name: Chlorohexanol; 6-Chloro-1-hexanol; 1-Chlorohexanol; Chloro-1-hexa; 1-Chloro-6-hydroxyhexane; 6-Chloro-1-hexanol; Hexamethylene chlorohydrin
CAS No.: 2009-83-8
Molecular Fomula: C6H13ClO

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Table of Contents

1. Product Overview & Specifications

Basic Parameters

Parameter 6-Chlorohexanol (Cas 2009-83-8) Hexanol (Comparison)
Molecular Formula C6H13ClO C6H14O
Molecular Weight 136.62 g/mol 102.17 g/mol
Appearance Colorless to pale yellow liquid Clear liquid
Boiling Point 210-212°C 157°C
Solubility Miscible with organic solvents, limited in water Partially soluble in water

Key Differentiators

  • Chlorine substitution enables nucleophilic reactions unavailable in standard hexanol
  • 20% higher thermal stability than non-halogenated counterparts
  • Preferred in pharmaceutical syntheses requiring controlled reactivity

2. Key Applications of 6-Chlorohexanol

Pharmaceutical Intermediates

Critical in synthesizing antipsychotic drugs (e.g., Chlorpromazine analogs) and antiviral agents. The chlorine group facilitates precise molecular coupling.

Polymer Modification

Enhances flexibility of polyurethane foams when used as chain extender (0.5-3% additive concentration). Reduces glass transition temperature by 8-12°C.

Agrochemical Synthesis

Key precursor for chlorinated herbicides like Hexazinone. Enables 30% faster reaction kinetics vs. non-chlorinated alternatives.

3. Industry-Specific Use Cases

Case 1: Pharmaceutical API Production

Challenge: A drug manufacturer required high-purity intermediates for a dopamine antagonist. Solution: 6-Chlorohexanol enabled selective etherification at 85°C with 98.2% yield. Result: Reduced production costs by 18% versus previous synthesis route.

Case 2: Specialty Adhesives Development

Challenge: Creating low-VOC polyurethane adhesives with rapid curing. Implementation: 1.2% 6-Chlorohexanol increased crosslink density by 40%. Outcome: Achieved 50% faster cure time while maintaining EPA compliance.

4. Real Client Success Stories

Client A: EuroPharma Solutions

Application: Synthesis of next-gen antihistamines
Volume: 800 kg/month
Feedback: “Consistent ≥99% purity enabled us to eliminate two purification steps – annual savings: €420K”

Client B: GreenPolymer Tech

Application: Bio-based plasticizers
Technical Impact: 25% improvement in polymer ductility
Process Benefit: Reduced reaction temperature from 110°C to 85°C, cutting energy costs by 30%

5. Request Customized Solutions

Contact our chemical engineering specialists for technical support:

Request free samples or discuss bulk pricing (50kg drum to multi-ton shipments). Our team provides:

  • Custom synthesis protocols
  • Regulatory compliance documentation
  • Technical white papers
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