1,6-Dichlorohexane (CAS 2163-00-0): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
1,6-Dichlorohexane (CAS 2163-00-0) is a halogenated alkane with the molecular formula C6H12Cl2. Widely used as a versatile intermediate in organic synthesis, it features:
Parameter | Specification |
---|---|
Molecular Weight | 155.06 g/mol |
Appearance | Clear colorless liquid |
Purity | ≥99% (GC analysis) |
Boiling Point | 210-212°C |
Density | 1.08 g/cm3 at 25°C |
Storage | 2-8°C in airtight containers |
2. Key Applications & Use Cases
Primary Industrial Uses:
- Pharmaceutical Intermediate: Synthesis of antihistamines and antispasmodic agents
- Polymer Production: Crosslinking agent for specialty rubbers
- Organic Synthesis: Alkylating agent in Grignard reactions
- Agrochemicals: Building block for pesticide formulations
Optimized Workflow Example (Pharma):
- Step 1: React with piperazine derivatives
- Step 2: Purify via fractional distillation
- Step 3: Characterize using NMR/HPLC
3. Industry-Specific Case Studies
Case 1: High-Performance Silicone Production
Challenge: Improve thermal stability of silicone polymers
Solution: 0.8% 1,6-Dichlorohexane additive increased decomposition temperature by 42°C
Result: Achieved UL 94 V-0 flame rating
Case 2: Pesticide Formulation
Challenge: Develop soil-stable insecticide
Solution: Used as chlorination agent in synthesis
Result: 18-month extended field efficacy
4. Competitive Parameter Comparison
Parameter | 1,6-Dichlorohexane | 1,5-Dichloropentane | 1,4-Dichlorobutane |
---|---|---|---|
Chain Length | C6 | C5 | C4 |
Reactivity | Moderate | High | Very High |
Thermal Stability | Excellent | Good | Fair |
5. Client Success Stories
Client A: European Pharma Manufacturer
Usage: Synthesized novel dopamine agonists
Volume: 2.5 MT/month
Outcome: 22% yield improvement vs previous process
Client B: Asian Polymer Company
Usage: Production of fuel-resistant O-rings
Volume: 6 MT/quarter
Outcome: Passed ASTM D471 oil immersion test
6. Request a Quote or Technical Support
Optimize your production with premium-grade 1,6-Dichlorohexane:
- Batch-to-batch consistency guaranteed
- Technical datasheets & SDS available
- Custom packaging solutions
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