Chemical Name: 4-Chlorobenzoic acid
Other Name: p-Carboxychlorobenzene; p-Chorobenzoic acid; Parachlorobenzoic acid
CAS No.: 74-11-3
Molecular Fomula: C7H5ClO2
Molecular weight: 156.57
Appearance: White Powder
Parameter | Specification |
---|---|
CAS Number | 74-11-3 |
Molecular Formula | C7H5ClO2 |
Molecular Weight | 156.57 g/mol |
Appearance | White crystalline powder |
Melting Point | 238-242°C |
Solubility | Soluble in ethanol, ether; slightly soluble in water |
Pharmaceutical Intermediate: Critical component in synthesis of antifungal agents and COX-2 inhibitors.
Agrochemical Production: Building block for chlorophenoxy herbicides and pesticide formulations.
Organic Synthesis: Versatile reagent for Friedel-Crafts reactions and carboxylation processes.
Compound | Reactivity | Thermal Stability | Cost Efficiency |
---|---|---|---|
4-Chlorobenzoic Acid | High | Excellent | $$$ |
Benzoic Acid | Moderate | Good | $ |
2-Chlorobenzoic Acid | Medium | Fair | $$ |
Storage: Maintain in airtight containers at 15-25°C with ≤65% humidity
Handling: Use NIOSH-approved respirators and chemical-resistant gloves
Reaction Optimization: Recommended molar ratios 1:1.2 with amine compounds
Challenge: Required high-purity intermediate for NSAID production
Solution: Implemented 99.8% purity 4-chlorobenzoic acid
Result: 22% yield improvement with 98.5% API purity
Challenge: Needed cost-effective herbicide precursor
Solution: Bulk procurement of technical-grade material
Result: Reduced production costs by 18% while maintaining efficacy
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