Chemical Name: 1,3-Dibromopropane
Other Name: Dibromo-1,3 propane; Trimethylene bromide
CAS No.: 109-64-8
Molecular Fomula: C3H6Br2
Molecular weight: 201.89
Appearance: Yellow or Colorless liquid
Parameter | 1,3-Dibromopropane | Common Alternatives |
---|---|---|
CAS Number | 109-64-8 | 78-75-1 (1,2-Dibromopropane) |
Molecular Formula | C3H6Br2 | C3H6Br2 |
Boiling Point | 167°C @ 760mmHg | 141°C (1,2-isomer) |
Flash Point | 54°C (Closed cup) | 47°C |
Vapor Density | 7 (Air=1) | 6.8 |
This organobromine compound serves critical functions in:
A European pharma manufacturer achieved 23% yield improvement in nucleoside analog production through optimized 1,3-dibromopropane coupling at 65-70°C with palladium catalysts.
Japanese researchers developed low-temperature cyclopropanation (45°C) maintaining 99.5% stereochemical purity using modified reaction stoichiometry.
Annual consumption: 8.5MT
Application: Thermally stable polymer cross-linker
Result: Achieved 40°C improvement in glass transition temperature
Annual consumption: 3.2MT
Application: Anticancer compound synthesis
Result: Reduced reaction steps from 7 to 4 in API production
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