Chemical Name: Diacerein
Synonyms: 1,8-Diacetoxy-3-carboxyanthraquinone; diacerhein
CAS No.: 13739-02-1
Molecular Formula: C19H12O8
Molecular Weight: 368.29
Parameter | Diacerein | Comparative Substance |
---|---|---|
CAS Number | 13739-02-1 | Glucosamine: 3416-24-8 |
Molecular Formula | C19H12O8 | C6H13NO5 |
Therapeutic Class | Interleukin-1 Inhibitor | Chondroprotective Agent |
Storage Conditions | 2-8°C (Desiccated) | Room Temperature |
Primary therapeutic applications in osteoarthritis management through:
Application | Concentration | Duration |
---|---|---|
Clinical Treatment | 50mg twice daily | 4-6 months |
Research Use | 10-100μM | 24-72 hours |
Challenge: Enhance bioavailability in oral delivery systems
Solution: Microencapsulation technology implementation
Result: 40% bioavailability improvement
Application: Osteoarthritis sustained-release formulation
Volume: 300kg annual consumption
Outcome: 18-month stability achievement
Application: Cartilage degeneration inhibition study
Concentration: 75μM solution
Finding: 62% IL-1β reduction
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