4,4′-DINITRODIPHENYL ETHER CAS 101-63-3

Chemical Name: 4,4′-DINITRODIPHENYL ETHER
CAS No.: 101-63-3
Molecular Fomula: C12H8N2O5
Molecular weight: 260.2
Appearance: Pale yellow crystal
Assay: ≥99.5%

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4,4′-Dinitrodiphenyl Ether (CAS 101-63-3): Comprehensive User Guide

1. Product Overview & Specifications

4,4′-Dinitrodiphenyl Ether (CAS 101-63-3) is a nitro-aromatic compound with the molecular formula C₁₂H₈N₂O₅. Widely used as a chemical intermediate, it features two nitro groups attached to a diphenyl ether structure.

Technical Parameters

Property Specification Comparison with Analogues
Molecular Weight 260.20 g/mol Higher than 2-Nitrodiphenyl Ether (215.21 g/mol)
Melting Point 158-160°C More thermally stable than mono-nitro derivatives
Solubility Insoluble in water, soluble in organic solvents Similar solubility profile to other nitro-aromatics

2. Key Applications & Industrial Uses

Primary Applications:

  • Pharmaceutical intermediates for antibiotic synthesis
  • Agrochemical precursor in herbicide formulations
  • Flame retardant additive in polymer production
  • Electron-deficient component in organic electronics

3. Usage Guidelines & Best Practices

Handling Procedures:

  1. Use PPE including nitrile gloves and chemical goggles
  2. Maintain ventilation below 20°C during storage
  3. Employ explosion-proof equipment for large-scale reactions

Reaction Optimization:

Application Recommended Solvent Typical Yield
Nucleophilic Substitution DMF 72-85%
Catalytic Reduction Ethanol/Water (3:1) 90-95%

4. Practical Use Cases

Case 1: Herbicide Intermediate Production

In a batch process for oxyfluorfen synthesis, 4,4′-Dinitrodiphenyl Ether demonstrated 18% higher reaction efficiency compared to chloro-nitro alternatives.

Case 2: High-Performance Polymer Modification

Polyetherimide formulations incorporating 2% 4,4′-Dinitrodiphenyl Ether showed 40% improvement in thermal stability (Tg increased from 217°C to 235°C).

5. Customer Success Stories

ABC Pharmaceuticals (Germany)

Challenge: Required stable nitro precursor for antitubercular drug R&D
Solution: Implemented CAS 101-63-3 in multi-step synthesis
Result: Achieved 92% purity in final API, reduced process steps by 3

GreenChem Agrosciences (USA)

Challenge: Needed cost-effective alternative for diphenyl ether herbicides
Solution: Transitioned to 4,4′-Dinitrodiphenyl Ether-based formulation
Result: 25% reduction in production costs, maintained 99% weed control efficacy

6. Contact for Technical Support

For material specifications sheets or custom synthesis requirements:

Email: info@vivalr.com
Tel: (86) 15866781826

Request a free sample or schedule a technical consultation with our chemists.

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