Parameter | Probenecid Sodium | Similar Compounds |
---|---|---|
CAS Number | 23795-03-1 | N/A |
Molecular Formula | C13H19NNaO4S | Varies by derivative |
Purity Grade | ≥99% (HPLC) | 70-98% typical |
Storage Conditions | 2-8°C in dark | Room temp (some analogs) |
• Uricosuric agent in gout treatment
• Antibiotic adjuvant for penicillin/cephalosporin therapies
• Clinical research in renal transport mechanisms
• Inhibitor of multidrug resistance proteins (MRP)
• Pharmacokinetic studies enhancement
• Animal model development for metabolic studies
Challenge: Improve cefalotin efficacy in renal-impaired models
Solution: 50mg/kg probenecid co-administration
Outcome: 62% increase in antibiotic half-life
Challenge: Quantify CNS drug penetration
Solution: MRP inhibition protocol
Outcome: Successful blood-brain barrier analysis model
Preparation Type | Concentration | Vehicle |
---|---|---|
In vitro studies | 10-100μM | DMSO/PBS |
Animal dosing | 25-150mg/kg | Saline solution |
Contact our pharmaceutical experts:
Email: info@vivalr.com
Phone: (86) 15866781826
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This is William, CEO of fousi chemical Chemical Co., Ltd.
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