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Specialized inD-Glucuronic acid Cas 6556-12-3and related product development and production

Chemical Name: D-Glucuronic acid
Cas No.: 6556-12-3
Molecular Fomula: C6H10O7
Molecular Weight: 194.14
Appearance: White to off-white crystalline powder

Samples: Available / Stock: Sufficient
Estimated delivery time: 3-5 days

D-Glucuronic Acid (CAS 6556-12-3): Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

D-Glucuronic Acid (CAS 6556-12-3) is a six-carbon sugar acid derived from glucose oxidation, featuring five hydroxyl groups and one carboxyl group. It is a critical component in glycosaminoglycans, glycoproteins, and detoxification processes.

Parameter Value
Molecular Formula C6H10O7
Molecular Weight 194.14 g/mol
Appearance White to off-white crystalline powder
Melting Point 159–161°C
Boiling Point 495.2°C (at 760 mmHg)
Density 1.6–2.0 g/cm³
Purity ≥98% (GC)
Storage Room temperature (4°C recommended for long-term stability)

2. Applications & Uses

Key Applications:

  • Drug Detoxification: Essential in Phase II metabolism, conjugating toxins via glucuronidation.
  • Biochemical Research: Used to study glycosaminoglycan synthesis (e.g., hyaluronic acid).
  • Pharmaceuticals: Intermediate in anticoagulants and anti-inflammatory drugs.
  • Cosmetics: Enhances skin hydration in hyaluronic acid-based products.

3. Usage Guidelines

Recommended Protocols:

  • Solubility: Dissolve in water (100 mg/mL) for clear solutions.
  • Handling: Store in airtight containers; avoid prolonged exposure to humidity.
  • Analytical Use: Compatible with GC, HPLC, and enzymatic assays.

4. Case Studies

Case 1: Drug Metabolism Analysis

A pharmaceutical company utilized D-Glucuronic Acid to study liver enzyme kinetics, achieving 95% conjugation efficiency in preclinical trials.

Case 2: Hyaluronic Acid Synthesis

A biotech firm integrated the compound into glycosaminoglycan production, improving yield by 30% in vitro.

5. Client Success Stories

Client A: Beijing Northern Weiya Measurement Technology Institute

Used D-Glucuronic Acid (Product Code: 1ST3247) as a reference standard for quality control in FDA-approved drug development.

Client B: Zhejiang Yuxiang Biotechnology Co., Ltd.

Supplied Sigma-Aldrich-grade D-Glucuronic Acid (CAS 6556-12-3) to research institutes for metabolic pathway studies.

6. Contact for Inquiries

For bulk orders, technical specifications, or custom synthesis:

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Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
5000+ square meters R&D center
A 70+ R&D team led by Chinese and foreign doctors
150 pieces (sets) of R&D equipment, 120+ fume hoods
18 patents

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
It has successfully passed on-site inspections from the United States, Australia, Poland, Japan and domestic pharmaceutical company customers and institutions many times, providing high-quality one-stop services for R&D and production of new drugs around the world.

More than 150 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

About the company

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FAQ

Does it support auditing?

Support, please make an appointment one day in advance. Company address: Room 716, Building 3, Ligao International Garden, No.1222 West Aoti Road, Lixia District, Jinan City, Shandong Province, P.R. China

Whether to provide samples?

Free samples can be provided for low value products, and small packaging specifications can be purchased for high value products.

Delivery time

Under normal circumstances, all items are in stock and will be shipped before 4 o'clock on the same day. Some products are produced to order, depending on the workshop situation and production schedule.

What is the production capacity?

At present, the company's workshop production equipment is mainly based on laboratories and pilot lines, with a maximum daily production capacity of 1.5 tons.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Chem-iso’s delivery rate is guaranteed to be 99.99%

5000+

square meter R&D center

150+

China(set) of R&D equipment

150+

Fume hood

180+

R&D team

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