D-Glucuronic acid Cas 6556-12-3

Chemical Name: D-Glucuronic acid
Cas No.: 6556-12-3
Molecular Fomula: C6H10O7
Molecular Weight: 194.14
Appearance: White to off-white crystalline powder

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D-Glucuronic Acid (CAS 6556-12-3): Comprehensive User Guide

1. Product Overview & Specifications

D-Glucuronic Acid (CAS 6556-12-3) is a six-carbon sugar acid derived from glucose oxidation, featuring five hydroxyl groups and one carboxyl group. It is a critical component in glycosaminoglycans, glycoproteins, and detoxification processes.

Parameter Value
Molecular Formula C6H10O7
Molecular Weight 194.14 g/mol
Appearance White to off-white crystalline powder
Melting Point 159–161°C
Boiling Point 495.2°C (at 760 mmHg)
Density 1.6–2.0 g/cm³
Purity ≥98% (GC)
Storage Room temperature (4°C recommended for long-term stability)

2. Applications & Uses

Key Applications:

  • Drug Detoxification: Essential in Phase II metabolism, conjugating toxins via glucuronidation.
  • Biochemical Research: Used to study glycosaminoglycan synthesis (e.g., hyaluronic acid).
  • Pharmaceuticals: Intermediate in anticoagulants and anti-inflammatory drugs.
  • Cosmetics: Enhances skin hydration in hyaluronic acid-based products.

3. Usage Guidelines

Recommended Protocols:

  • Solubility: Dissolve in water (100 mg/mL) for clear solutions.
  • Handling: Store in airtight containers; avoid prolonged exposure to humidity.
  • Analytical Use: Compatible with GC, HPLC, and enzymatic assays.

4. Case Studies

Case 1: Drug Metabolism Analysis

A pharmaceutical company utilized D-Glucuronic Acid to study liver enzyme kinetics, achieving 95% conjugation efficiency in preclinical trials.

Case 2: Hyaluronic Acid Synthesis

A biotech firm integrated the compound into glycosaminoglycan production, improving yield by 30% in vitro.

5. Client Success Stories

Client A: Beijing Northern Weiya Measurement Technology Institute

Used D-Glucuronic Acid (Product Code: 1ST3247) as a reference standard for quality control in FDA-approved drug development.

Client B: Zhejiang Yuxiang Biotechnology Co., Ltd.

Supplied Sigma-Aldrich-grade D-Glucuronic Acid (CAS 6556-12-3) to research institutes for metabolic pathway studies.

6. Contact for Inquiries

For bulk orders, technical specifications, or custom synthesis:

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