3-Thiophenecarboxaldehyde CAS 498-62-4

Chemical Name: 3-Thiophenecarboxaldehyde
Cas No.: 498-62-4
Molecular Fomula: C5H4OS
Molecular Weight: 112.15
Appearance: Colorless to yellow liquid

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3-Thiophenecarboxaldehyde (CAS 498-62-4) Comprehensive Guide

1. Product Specifications & Comparative Analysis

Parameter 3-Thiophenecarboxaldehyde Typical Aldehyde Derivatives
CAS Number 498-62-4 Varies by compound
Molecular Formula C5H4OS CnH2nO
Molecular Weight 112.15 g/mol 90-150 g/mol
Boiling Point 198°C at 760 mmHg 150-250°C
Flash Point 73°C (163°F) 60-100°C
Solubility Miscible with alcohols, ethers; Limited water solubility Polar solvent compatible

Key differentiators include enhanced thermal stability and distinct electronic properties due to thiophene heterocycle integration.

2. Functional Applications

This heterocyclic aldehyde serves as critical building block in:

  • Pharmaceutical intermediates (ACE inhibitors, antipsychotics)
  • Organic electronic materials (OLED charge transport layers)
  • Coordination chemistry (ligand synthesis)
  • Agrochemical research (pesticide derivatives)

3. Implementation Scenarios

Typical process integration:

  1. Schiff base formation: Reacts with primary amines at 60-80°C
  2. Nucleophilic addition: Grignard reagent reactions in THF
  3. Cross-coupling: Suzuki reactions with aryl boronic acids

4. Industry Case Studies

Case 1: Pharmaceutical Intermediate Production

Wuhan Hongteng Hengrui Chemical utilized 98% purity grade material to develop antihypertensive drug precursors, achieving 92% reaction yield under optimized Buchwald-Hartwig conditions.

Case 2: Organic Semiconductor Development

Shanghai Xinyu Biotech synthesized thiophene-based conjugated polymers showing 15% improved charge mobility compared to furan analogs in OLED prototypes.

5. Procurement Consultation

Available specifications:

  • Purity grades: 95%, 98%, 99% (HPLC)
  • Packaging: 1kg glass bottles to 200kg HDPE drums
  • Custom synthesis: Halogenated derivatives available

Contact technical team for material selection guidance:
Email: info@vivalr.com
Tel: (86) 15866781826

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