Bis(triphenylphosphine)copper(I) Chloride Cas 25577-10-0

Chemical Name :bis(triphenylphosphine)copper(I) chloride
CAS No.: 25577-10-0
Molecular Fomula:C36H30ClCuP2

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Bis(triphenylphosphine)copper(I) Chloride (CAS 25577-10-0) User Guide

1. Product Overview & Parameter Comparison

Bis(triphenylphosphine)copper(I) Chloride (CAS 25577-10-0) is a highly stable copper(I) complex widely used in organic synthesis and catalysis. Key parameters:

Parameter Specification
CAS Number 25577-10-0
Molecular Formula C36H30ClCuP2
Molecular Weight 656.56 g/mol
Appearance White to off-white crystalline powder
Solubility Soluble in THF, DCM; insoluble in water
Storage 2-8°C, under inert atmosphere

Comparison with Similar Copper Complexes

Feature Bis(triphenylphosphine)CuCl CuCl(PPh3)3 [Cu(acac)PPh3]
Stability High Moderate Low
Catalytic Activity Excellent in cross-coupling Limited scope Thermosensitive
Solubility Broad solvent compatibility Polar solvents only Narrow range

2. Detailed Applications

  • Catalysis: Key catalyst for Ullmann couplings, Sonogashira reactions, and C-N bond formations.
  • Ligand in Polymerization: Stabilizes copper centers in conductive polymer synthesis.
  • Photoresist Materials: Enhances sensitivity in UV-curable coatings.
  • Electronics: Used in OLEDs as an electron transport layer precursor.

3. Usage Guidelines

Typical Reaction Setup (Suzuki-Miyaura Coupling)

  1. Add 0.1 mol% of Bis(triphenylphosphine)CuCl to a dry flask.
  2. Charge with aryl halide (1.0 eq), boronic acid (1.2 eq), and base (2.0 eq).
  3. Use THF as solvent; reflux under N2 for 6-12 hours.
  4. Isolate product via column chromatography (yield: 85-92%).

4. Case Studies

Case 1: Conductive Polymer Synthesis

Challenge: Achieve high conductivity in polythiophene films.
Solution: 0.05% Bis(triphenylphosphine)CuCl increased polymerization rate by 40% and reduced defects.

Case 2: Pharmaceutical Intermediate

Challenge: Low yield in aryl ether formation.
Solution: Catalyst reduced reaction time from 24h to 8h with 88% yield.

5. Client Success Stories

PharmaSynth Inc. (USA)

“Using Bis(triphenylphosphine)CuCl accelerated our API synthesis by 30%, saving $220k annually in production costs.”

PolymerTech Co., Ltd. (Germany)

“The compound’s stability under harsh conditions enabled us to develop high-performance OLED materials with 15% efficiency gains.”

6. Request a Quote

Contact our technical team for customized solutions:

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