4-Acetylbiphenyl Cas 92-91-1

Chemical Name: 4-Acetylbiphenyl
Synonyms: 4′-Phenylacetophenone; 4-Biphenyl methyl ketone; 4-biphenylyl methyl keton; p-phenylacetophenone; acetylbiphenyl
CAS No.: 92-91-1
Molecular Fomula: C14H12O
Molecular weight: 196.24
Appearance: White crystal powder
Assay:≥99.0%

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4-Acetylbiphenyl (CAS 92-91-1) Comprehensive Guide

Table of Contents

Product Specifications

Parameter Detail
Chemical Name 4-Acetylbiphenyl
CAS Number 92-91-1
Molecular Formula C14H12O
Molecular Weight 196.25 g/mol
Appearance White crystalline powder
Purity ≥99% (HPLC)
Melting Point 118-121°C
Boiling Point 365.8°C at 760 mmHg
Solubility Soluble in organic solvents (DMSO, ethanol)

Industrial Applications

Pharmaceutical Intermediate

Critical precursor for COX-2 inhibitor APIs and oncology drug candidates. Enables precise acetyl group introduction in steroid synthesis.

Advanced Material Synthesis

Essential component in:
– Liquid crystal display (LCD) manufacturing
– OLED electron transport layers
– Photosensitive polyimide production

Comparative Analysis

Feature 4-Acetylbiphenyl 4-Acetyltoluene 4-Acetylphenol
Thermal Stability Excellent (Up to 300°C) Moderate Poor
Reactivity Controlled acetyl transfer High volatility Oxidation prone

Operational Protocols

Handling Requirements

1. Store in nitrogen-purged containers at 2-8°C
2. Use anhydrous conditions for sensitive reactions
3. Recommended solvent: HPLC-grade DMSO

Implementation Examples

Case 1: Anticancer Drug Development

Used as key building block in kinase inhibitor R&D by major pharma company, achieving 92% reaction yield.

Case 2: Flexible Display Production

Enabled 15% efficiency improvement in foldable OLED manufacturing for leading electronics supplier.

Client Success Stories

PharmaSynth Co., Ltd. (Germany)

“Achieved 40% cost reduction in anti-inflammatory API production through optimized acetylation processes using 4-Acetylbiphenyl.”

TechMaterials Inc. (USA)

“Critical component in our next-gen display materials development cycle, reduced synthesis steps from 7 to 4.”

Technical Support & Quotations

Contact our chemistry experts:
Email: info@vivalr.com
Tel: (86) 15866781826

Request free samples or bulk pricing: Specify required quantity and application details.

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