Chemical Name: 4-Acetylbiphenyl
Synonyms: 4′-Phenylacetophenone; 4-Biphenyl methyl ketone; 4-biphenylyl methyl keton; p-phenylacetophenone; acetylbiphenyl
CAS No.: 92-91-1
Molecular Fomula: C14H12O
Molecular weight: 196.24
Appearance: White crystal powder
Assay:≥99.0%
Parameter | Detail |
---|---|
Chemical Name | 4-Acetylbiphenyl |
CAS Number | 92-91-1 |
Molecular Formula | C14H12O |
Molecular Weight | 196.25 g/mol |
Appearance | White crystalline powder |
Purity | ≥99% (HPLC) |
Melting Point | 118-121°C |
Boiling Point | 365.8°C at 760 mmHg |
Solubility | Soluble in organic solvents (DMSO, ethanol) |
Critical precursor for COX-2 inhibitor APIs and oncology drug candidates. Enables precise acetyl group introduction in steroid synthesis.
Essential component in:
- Liquid crystal display (LCD) manufacturing
- OLED electron transport layers
- Photosensitive polyimide production
Feature | 4-Acetylbiphenyl | 4-Acetyltoluene | 4-Acetylphenol |
---|---|---|---|
Thermal Stability | Excellent (Up to 300°C) | Moderate | Poor |
Reactivity | Controlled acetyl transfer | High volatility | Oxidation prone |
1. Store in nitrogen-purged containers at 2-8°C
2. Use anhydrous conditions for sensitive reactions
3. Recommended solvent: HPLC-grade DMSO
Used as key building block in kinase inhibitor R&D by major pharma company, achieving 92% reaction yield.
Enabled 15% efficiency improvement in foldable OLED manufacturing for leading electronics supplier.
"Achieved 40% cost reduction in anti-inflammatory API production through optimized acetylation processes using 4-Acetylbiphenyl."
"Critical component in our next-gen display materials development cycle, reduced synthesis steps from 7 to 4."
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