N-Ethyl-3-carbazolecarboxaldehyde (CAS 7570-45-8) User Guide: Applications, Case Studies & Technical Insights
Table of Contents
1. Product Overview & Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 7570-45-8 |
| Molecular Formula | C15H13NO |
| Purity | ≥98% (HPLC) |
| Appearance | Pale yellow crystalline powder |
| Melting Point | 142-145°C |
2. Key Applications & Industry Uses
Pharmaceutical Intermediates
Critical precursor for antitumor agents and kinase inhibitors due to carbazole’s electron-rich structure.
OLED Materials
Enhances hole-transport efficiency in organic light-emitting diodes (tested at 15% improved luminance vs. standard ETLs).
Polymer Modification
Increases thermal stability in polyimide films (Tg improvement: 20-25°C at 2% loading).
3. Operational Guidelines & Best Practices
Storage Protocols
Maintain at 2-8°C in amber glass under inert gas (argon preferred). Shelf life: 24 months unopened.
Reaction Conditions
Optimal Suzuki coupling performance: 80-100°C in THF/water (4:1) with Pd(PPh3)4 catalyst.
4. Comparative Analysis with Alternatives
| Parameter | N-Ethyl-3-carbazolecarboxaldehyde | 9-Phenylcarbazole | 3,6-Dibromocarbazole |
|---|---|---|---|
| Electrophilic Reactivity | High (aldehyde group) | Low | Medium |
| OLED Performance | HTL Efficiency: 92% | 88% | 85% |
5. Verified Customer Success Stories
Case 1: Shanghai MedChem Co., Ltd.
Application: PARP inhibitor intermediate synthesis
Result: 40% yield improvement vs. previous carbazole derivatives
Case 2: Shenzhen OLED Material Tech
Application: Blue OLED host material
Outcome: 18% lower operating voltage at 1000 cd/m²
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