Chemical Name: Dithioerythritol
Synonyms: dithioerythreitol; dl-dithioerythritol; erythro-1,4-Dimercapto-2,3-butanediol
CAS No.: 6892-68-8
Molecular Fomula: C4H10O2S2
Molecular weight: 154.25
Appearance: White to light yellow powder
Assay:≥98.0%
Parameter | Dithioerythritol (DTE) | DTT (Common Alternative) |
---|---|---|
CAS Number | 6892-68-8 | 3483-12-3 |
Molecular Formula | C4H10O2S2 | C4H10O2S2 |
Reduction Efficiency | High (Dual thiol groups) | Moderate |
Stability in Solution | 72 hours (4°C) | 48 hours (4°C) |
Recommended Storage | -20°C in anhydrous form | 2-8°C |
Core Function: Protein disulfide bond reduction in biochemical research
Case A: Vaccine Production Workflow
Process Stage | DTE Concentration | Result Optimization |
---|---|---|
Viral Protein Isolation | 5-10 mM | 93% Activity Preservation |
Lyophilization | 2 mM + 5% Trehalose | 18-month Stability |
Customer 1: Biologics Manufacturer (Shanghai)
Customer 2: Contract Research Organization (Boston)
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