Table of Contents
- 2,5-Thiophenedicarboxylic Acid Overview
- Parameter Comparison
- Key Applications
- Usage Guidelines
- Industry Case Studies
- Contact Supplier
2,5-Thiophenedicarboxylic Acid (CAS 4282-31-9) Overview
Basic Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 4282-31-9 |
| Molecular Formula | C6H4O4S |
| Molecular Weight | 172.16 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Melting Point | 280-285°C (dec.) |
| Solubility | Soluble in DMF, DMSO; sparingly soluble in water |
Comparative Analysis
| Feature | 2,5-Thiophenedicarboxylic Acid | Other Dicarboxylic Acids |
|---|---|---|
| Electron Density | High (thiophene ring) | Variable |
| Thermal Stability | Excellent (up to 300°C) | 200-250°C typical |
| Coordination Capacity | Dual carboxyl groups | Single/multiple varies |
| Pharma Compatibility | FDA-approved intermediates | Limited applications |
Industrial Applications
Pharmaceutical Intermediate
Key component in synthesizing:
- Tyrosine kinase inhibitors
- Anticancer drug precursors
- Non-steroidal anti-inflammatory agents
Advanced Material Science
- MOFs (Metal-Organic Frameworks)
- Conductive polymers for OLEDs
- Coordination polymers
Operational Guidelines
Storage Conditions
| Parameter | Requirement |
|---|---|
| Temperature | 2-8°C (long-term) |
| Humidity | <40% RH |
| Light Exposure | Amber glass containers |
Reaction Protocol
- Use anhydrous DMF as solvent
- Maintain nitrogen atmosphere
- Optimal reaction temperature: 80-100°C
Client Implementations
Case Study 1: Oncology Drug Development
Client: Top 10 Global Pharma Company
- Application: EGFR inhibitor intermediate
- Result: 92% yield improvement vs previous synthesis
- Scale: 500kg batch production
Case Study 2: Flexible Electronics
Client: OLED Manufacturer
- Application: Electron transport layer material
- Performance: 15% efficiency increase
- Patent Status: US 11,235,678 B2
Contact Our Experts
Request technical documents or pricing:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Custom synthesis available from gram to ton scale.
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