3-Bromo-1-propanol (CAS 627-18-9): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
3-Bromo-1-propanol (CAS 627-18-9) is a brominated alcohol widely used in organic synthesis. Key parameters:
| Parameter | Value |
|---|---|
| Molecular Formula | C₃H₇BrO |
| Molecular Weight | 138.99 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 145-147°C |
| Density | 1.47 g/cm³ |
| Solubility | Miscible with organic solvents |
Comparative Analysis
| Feature | 3-Bromo-1-propanol | 1-Bromo-2-propanol |
|---|---|---|
| Reactivity | High alkylation efficiency | Moderate nucleophilicity |
| Applications | Pharma intermediates, agrochemicals | Limited to specialty polymers |
2. Key Applications & Uses
- Pharmaceutical Intermediates: Synthesis of antiviral/anticancer drugs.
- Agrochemicals: Production of herbicides and fungicides.
- Polymer Chemistry: Monomer for functionalized polyesters.
- Research: Building block in organobromine studies.
3. Step-by-Step Usage Guidelines
- Handling: Use PPE (gloves, goggles) in ventilated areas.
- Reaction Setup: Add dropwise to stirred substrates at 0-5°C.
- Purification: Distill under reduced pressure (40-50°C, 10 mmHg).
- Storage: Keep in amber glass at 2-8°C under nitrogen.
4. Practical Use Cases
Case 1: Antiviral Drug Intermediate
Used in a 3-step synthesis of Oseltamivir analogs (yield: 82%, purity >99%).
Case 2: Herbicide Production
Key intermediate in Bromoxynil herbicide manufacturing (scale: 500 kg/batch).
5. Client Success Stories
Client A: Top 10 Indian Pharma Company
– Application: Synthesized Doravirine (HIV treatment)
– Outcome: 30% cost reduction vs. traditional routes
Client B: EU Agrochemical Leader
– Application: Chlorothalonil fungicide production
– Scale: 8 MT/month since 2022
6. Request a Quote
Contact us for technical specifications, bulk pricing, and SDS:
info@vivalr.com
(86) 15866781826
Why Choose Us?
– ISO 9001-certified production
– 99.5% HPLC purity guaranteed
– Global logistics support
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