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Specialized inDeoxythymidine triphosphate CAS 18423-43-3and related product development and production

Chemical Name: Deoxythymidine triphosphate
Synonyms: 2′-Deoxythymidine 5′-triphosphate
CAS No.: 18423-43-3
Molecular Fomula: C10H18N2NaO14P3
Molecular weight: 506.17

Samples: Available / Stock: Sufficient
Estimated delivery time: 3-5 days

Table of Contents

Deoxythymidine Triphosphate (dTTP) CAS 18423-43-3: Product Information & Specifications

Basic Parameters

Parameter Specification
CAS Number 18423-43-3
Molecular Formula C10H17N2O14P3
Molecular Weight 502.15 g/mol
Purity ≥99% (HPLC)
Storage -20°C, desiccated

Comparative Analysis of dTTP Grades

Feature Analytical Grade Molecular Biology Grade
Endotoxin Level <10 EU/mg <1 EU/mg
DNase/RNase Activity Not tested Undetectable
Typical Applications Basic research PCR, sequencing

Detailed Applications of dTTP in Biotechnology

Core Applications

  • PCR Amplification: Critical component in DNA polymerase-driven amplification.
  • DNA Sequencing: Used in Sanger sequencing for chain termination.
  • cDNA Synthesis: Essential for reverse transcription processes.
  • Site-Directed Mutagenesis: Facilitates precise genetic modifications.

Emerging Uses

  • CRISPR-Cas9 genome editing workflows
  • NGS library preparation
  • Single-cell sequencing protocols

Optimal Usage Guidelines

Best Practices

  • Maintain strict cold chain during transport
  • Use nuclease-free buffers for dilution
  • Avoid repeated freeze-thaw cycles

Common Pitfalls

  • Contamination from non-sterile handling
  • Degradation due to improper pH conditions
  • Incorrect concentration in master mixes

Industry Case Studies

Case 1: Diagnostic Kit Development

Client: European Molecular Diagnostics Lab
Challenge: Required ultra-pure dTTP for COVID variant detection assays
Solution: Supplied molecular biology-grade dTTP with batch-specific QC reports
Outcome: 40% improvement in assay sensitivity

Case 2: Agricultural Genomics Research

Client: US Agri-Biotech Firm
Challenge: Needed stable dNTPs for field-deployable PCR systems
Solution: Custom lyophilized formulations with 18-month stability
Outcome: Enabled onsite crop pathogen detection

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This is William, CEO of fousi chemical Chemical Co., Ltd.

Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.

Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
5000+ square meters R&D center
A 70+ R&D team led by Chinese and foreign doctors
150 pieces (sets) of R&D equipment, 120+ fume hoods
18 patents

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
It has successfully passed on-site inspections from the United States, Australia, Poland, Japan and domestic pharmaceutical company customers and institutions many times, providing high-quality one-stop services for R&D and production of new drugs around the world.

More than 150 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

About the company

International Standard Chemicals Sell To All Over The World

FAQ

Does it support auditing?

Support, please make an appointment one day in advance. Company address: Room 716, Building 3, Ligao International Garden, No.1222 West Aoti Road, Lixia District, Jinan City, Shandong Province, P.R. China

Whether to provide samples?

Free samples can be provided for low value products, and small packaging specifications can be purchased for high value products.

Delivery time

Under normal circumstances, all items are in stock and will be shipped before 4 o'clock on the same day. Some products are produced to order, depending on the workshop situation and production schedule.

What is the production capacity?

At present, the company's workshop production equipment is mainly based on laboratories and pilot lines, with a maximum daily production capacity of 1.5 tons.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Chem-iso’s delivery rate is guaranteed to be 99.99%

5000+

square meter R&D center

150+

China(set) of R&D equipment

150+

Fume hood

180+

R&D team

User’evaluation of us

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Michael Cooper

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James Black

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Lisa Goodwill

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