3-Diethylamino-1-propanol Cas 622-93-5

Chemical Name: 3-Diethylamino-1-propanol
CAS No.: 622-93-5
Molecular Fomula: C7H17NO

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3-Diethylamino-1-propanol (CAS 622-93-5): Product Overview

3-Diethylamino-1-propanol (CAS 622-93-5) is a tertiary amine compound widely used in pharmaceuticals, agrochemicals, and polymer industries. Its molecular formula is C7H17NO, with a molecular weight of 131.22 g/mol. This colorless to pale yellow liquid exhibits high solubility in organic solvents and water, making it versatile for synthesis and catalysis.

Key Parameters

Parameter Value
CAS Number 622-93-5
Purity ≥98%
Boiling Point 190-192°C
Density 0.89 g/cm³
Flash Point 72°C
Storage 2-8°C, airtight container

Specifications & Comparative Analysis

Performance Comparison with Similar Amines

Compound Reactivity Solubility Cost Efficiency
3-Diethylamino-1-propanol High Excellent Moderate
DMAP Moderate Good High
DIPEA High Limited High

*DMAP: 4-Dimethylaminopyridine; DIPEA: N,N-Diisopropylethylamine

Applications & Industry Use Cases

1. Pharmaceutical Intermediates

Used as a building block in antibiotics, antivirals, and antihistamines due to its ability to facilitate nucleophilic substitutions.

2. Polymer Catalysis

Acts as a catalyst in polyurethane foam production, enhancing crosslinking efficiency and thermal stability.

3. Agrochemical Synthesis

Key intermediate in herbicides and insecticides, improving reaction yields by 15-20% compared to alternatives.

4. Dye Manufacturing

Enables pH stabilization in reactive dye formulations, ensuring color consistency.

Usage Guidelines & Safety

Handling Precautions

  • Wear PPE (gloves, goggles, lab coat)
  • Avoid inhalation/contact with skin
  • Use in well-ventilated areas

Storage

Store in sealed containers under inert gas (N2 or Ar) to prevent oxidation. Shelf life: 24 months.

Client Case Studies

Case 1: Pharmaceutical Manufacturer (Europe)

Challenge: Low yield (58%) in beta-lactam antibiotic synthesis.
Solution: Replaced triethylamine with 3-Diethylamino-1-propanol.
Result: Yield increased to 82%; reduced reaction time by 30%.

Case 2: Polymer Producer (USA)

Challenge: Inconsistent foam density in polyurethane products.
Solution: 0.5% 3-Diethylamino-1-propanol added as co-catalyst.
Result: Density variation reduced from ±12% to ±3%.

Case 3: Agrochemical Company (India)

Challenge: High impurity levels in glyphosate intermediate.
Solution: Optimized reaction with 3-Diethylamino-1-propanol at 65°C.
Result: Impurities decreased from 8% to 1.2%; production cost lowered by $12/kg.

Contact for Quotation & Technical Support

Email: info@vivalr.com
Phone: (86) 15866781826

Request a free sample or detailed MSDS by contacting our team. Custom synthesis and bulk pricing available.

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