Table of Contents
- Product Overview & Specifications
- Key Applications
- Industry Case Studies
- Client Success Stories
- Contact for Technical Consultation
Methoxypolyethylene Glycol Amine (CAS 80506-64-5) Specifications
Technical Parameters
| Property | Specification | Comparison with mPEG-SH | Comparison with mPEG-COOH |
|---|---|---|---|
| Molecular Weight Range | 350 Da – 40,000 Da | Similar molecular flexibility | Higher amine reactivity |
| Purity | ≥95% (HPLC) | Comparable purity standards | Superior conjugation efficiency |
| End Group Functionality | Primary amine (-NH2) | Thiol group (-SH) | Carboxylic acid (-COOH) |
Storage & Handling
Store at -20°C under nitrogen atmosphere. Shelf life: 24 months when properly stored. Incompatible with strong oxidizing agents.
Functional Applications
Pharmaceutical Applications
1. Drug conjugation for enhanced solubility
2. PEGylation of therapeutic proteins
3. Nanocarrier surface functionalization
Biotechnology Uses
• Biomolecule immobilization
• Diagnostic probe modification
• Tissue engineering scaffolds
Implementation Case Studies
Case 1: Targeted Drug Delivery System
Challenge: Improve tumor accumulation of chemotherapeutic agent
Solution: Conjugated mPEG-NH2 (5,000 Da) to nanoparticle surface
Result: 68% increase in circulation half-life
Case 2: Protein Stabilization
Challenge: Prevent enzyme aggregation
Method: Site-specific PEGylation using CAS 80506-64-5
Outcome: Maintained 92% activity after 6-month storage
Client Implementation Examples
Pharma Client A: Novel ADC Development
Application: Antibody-drug conjugate linker
Molecular Weight: 2,000 Da
Scale: 15kg batch production
Result: Achieved DAR 3.8 with 98% purity
Biotech Client B: Diagnostic Kit Enhancement
Use: Lateral flow assay modification
Specification: 10,000 Da MW
Performance: Increased detection sensitivity by 40%
Technical Consultation & Ordering
Contact our PEGylation experts for:
• Custom molecular weight options
• Bulk production requests
• Technical documentation support
Email: info@vivalr.com
Phone: (86) 15866781826
Request Product Documentation
Available upon request:
• COA (Certificate of Analysis)
• MSDS (Material Safety Data Sheet)
• Custom synthesis protocols



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