N-ethyl-2-nitrobenzenesulfonamine CAS 23530-41-8

Chemical Name: N-ethyl-2-nitrobenzenesulfonamine
CAS No.: 23530-41-8
Molecular Formula: C8H10N2O4S
Molecular Weight: 230.24
Appearance: White to light yellow crystals

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Table of Contents

Product Overview & Specifications

Basic Parameters

Parameter Value
CAS Number 23530-41-8
Molecular Formula C8H10N2O4S
Molecular Weight 230.24 g/mol
Appearance Yellow crystalline powder
Purity ≥98% (HPLC)
Storage Conditions 2-8°C in airtight container

Comparative Analysis

Feature N-ethyl-2-nitrobenzenesulfonamine Similar Derivatives
Reactivity High electrophilic substitution Moderate in non-nitrated analogs
Thermal Stability Stable up to 150°C Decomposes at 100-120°C

Applications of N-ethyl-2-nitrobenzenesulfonamine

Pharmaceutical Intermediates

Key precursor in ACE inhibitor synthesis, enabling precise stereochemical control in antihypertensive drug manufacturing.

Agrochemical Synthesis

Critical component in nitro-group-containing herbicide formulations, enhancing bioavailability by 30-40% compared to traditional sulfonamides.

Usage Guidelines

Reaction Optimization

Recommended dosage: 1.2-1.5 molar equivalents in nucleophilic aromatic substitution reactions. Maintain pH 7-8 for optimal yield.

Safety Protocols

Requires PPE including nitrile gloves and vapor respirator. NFPA rating: Health 2, Flammability 1, Reactivity 1.

Industry Case Studies

Pharmaceutical Manufacturing

Enabled 92% yield improvement in valsartan intermediate synthesis for Top 10 global pharma company.

Polymer Chemistry

Implemented as electron-deficient monomer in advanced polyether sulfone membranes for water treatment systems.

Client Success Stories

Case 1: Specialty Chemical Producer

Client: European fine chemicals manufacturer
Challenge: Needed stable nitro-group donor for high-temperature reactions
Solution: Custom micronized formulation of CAS 23530-41-8
Result: Achieved 99.5% reaction consistency at 130°C

Case 2: Research Institution

Client: University materials science lab
Application: Developing conductive polymer composites
Outcome: Enabled 15% conductivity enhancement in PEDOT-based systems

Contact for Technical Support

Email: info@vivalr.com
Phone: (86) 15866781826
Request custom synthesis scale-up protocols or MSDS documentation.

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