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Specialized in2-Bromo-9,9-dimethylfluorene CAS 28320-31-2and related product development and production

Chemical Name: 2-Bromo-9,9-dimethylfluorene
CAS No.: 28320-31-2
Molecular Fomula: C15H13Br
Molecular weight: 273.17
Appearance: White powder
Assay: ≥99%

Samples: Available / Stock: Sufficient
Estimated delivery time: 3-5 days

2-Bromo-9,9-dimethylfluorene (CAS 28320-31-2): Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

1.1 Chemical Profile

2-Bromo-9,9-dimethylfluorene (CAS 28320-31-2) is a brominated fluorene derivative with a molecular formula of C15H13Br. This organobromine compound features a dimethyl-substituted fluorene backbone, making it a critical intermediate in advanced organic synthesis.

1.2 Key Specifications

Parameter Specification 2-Bromofluorene 9,9-Dimethylfluorene
Molecular Weight 273.17 g/mol 245.08 g/mol 208.26 g/mol
Melting Point 98-102°C 153-155°C 185-187°C
Thermal Stability Excellent Moderate High

*Comparative data highlights enhanced stability and reactivity vs. similar compounds.

2. Key Applications & Use Cases

2.1 OLED Material Synthesis

Widely used as a precursor for hole-transport layers (HTL) in OLED displays. The dimethyl groups improve electron mobility while the bromine atom enables efficient cross-coupling reactions.

2.2 Pharmaceutical Intermediates

Essential in synthesizing kinase inhibitors and anticancer agents. The bromine site facilitates Suzuki-Miyaura couplings for biaryl drug candidates.

2.3 Polymer Additives

Enhances thermal stability in engineering plastics when incorporated into polyfluorene backbones at 0.5-2% w/w concentrations.

3. Industry Case Studies

3.1 OLED Manufacturer Case

Client: TechNova Displays (Shenzhen)
Challenge: Required a HTL material with ≥90% luminous efficiency at 150°C.
Solution: Synthesized customized derivatives using 2-Bromo-9,9-dimethylfluorene.
Result: Achieved 92% efficiency with 15% lower power consumption.

3.2 Pharmaceutical Research Case

Client: BioGen Therapeutics (Boston)
Challenge: Needed scalable synthesis of a BTK inhibitor intermediate.
Solution: Optimized Buchwald-Hartwig amination using our compound.
Result: Reduced reaction steps from 5 to 3, achieving 85% yield at kilo-scale.

4. Technical Support & Inquiry

Our team provides:

  • Custom synthesis (purity 98-99.9%)
  • Technical documentation (CoA, MSDS)
  • Process optimization support

Contact for Pricing/Samples:
Email: info@vivalr.com
Phone: (86) 15866781826

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Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
5000+ square meters R&D center
A 70+ R&D team led by Chinese and foreign doctors
150 pieces (sets) of R&D equipment, 120+ fume hoods
18 patents

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
It has successfully passed on-site inspections from the United States, Australia, Poland, Japan and domestic pharmaceutical company customers and institutions many times, providing high-quality one-stop services for R&D and production of new drugs around the world.

More than 150 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

About the company

International Standard Chemicals Sell To All Over The World

FAQ

Does it support auditing?

Support, please make an appointment one day in advance. Company address: Room 716, Building 3, Ligao International Garden, No.1222 West Aoti Road, Lixia District, Jinan City, Shandong Province, P.R. China

Whether to provide samples?

Free samples can be provided for low value products, and small packaging specifications can be purchased for high value products.

Delivery time

Under normal circumstances, all items are in stock and will be shipped before 4 o'clock on the same day. Some products are produced to order, depending on the workshop situation and production schedule.

What is the production capacity?

At present, the company's workshop production equipment is mainly based on laboratories and pilot lines, with a maximum daily production capacity of 1.5 tons.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Chem-iso’s delivery rate is guaranteed to be 99.99%

5000+

square meter R&D center

150+

China(set) of R&D equipment

150+

Fume hood

180+

R&D team

User’evaluation of us

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