2,4-Difluorobenzylamine (CAS 72235-52-0) Comprehensive Technical Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 2,4-Difluorobenzylamine | Standard Benzylamine |
|---|---|---|
| CAS Number | 72235-52-0 | 100-46-9 |
| Molecular Formula | C7H7F2N | C7H9N |
| Molecular Weight | 143.13 g/mol | 107.15 g/mol |
| Boiling Point | 82-84°C (15 mmHg) | 185°C |
| Density | 1.204 g/cm³ | 0.981 g/cm³ |
| Refractive Index | 1.490-1.493 | 1.540 |
| Hazard Class | 8 (Corrosive) | 3 (Flammable) |
Storage Requirements: Maintain in dark conditions under inert atmosphere at 2-8°C. UN Transport Code: 2735.
2. Functional Applications
This fluorinated benzylamine derivative serves as a critical intermediate in:
- Pharmaceutical synthesis (e.g., Mirabegron API production)
- Advanced material engineering
- Organofluorine compound development
- Specialty chemical manufacturing
3. Operational Protocols
Handling Requirements:
- Utilize chemical-resistant PPE (nitrile gloves, face shield)
- Implement local exhaust ventilation
- Prohibit eating/drinking in work areas
Emergency Procedures:
- Eye Contact: Flush with water for 15 minutes (remove contact lenses)
- Skin Contact: Remove contaminated clothing, wash with soap/water
- Fire: Use dry chemical or alcohol-resistant foam
4. Industry Use Cases
| Application Sector | Implementation | Performance Benefit |
|---|---|---|
| Pharmaceuticals | Overactive bladder medication synthesis | Enhanced bioactivity |
| Agrochemicals | Fluorinated pesticide intermediates | Improved metabolic stability |
5. Client Success Stories
Case Study 1: Major API Manufacturer
Challenge: Required high-purity (>99%) fluorinated intermediate for GMP production.
Solution: Custom synthesis with strict QC protocols.
Outcome: 30% yield improvement vs. previous suppliers.
Case Study 2: Research Institution
Challenge: Needed small-batch quantities for drug discovery.
Solution: Flexible 100g-1kg scaling with analytical documentation.
Outcome: Accelerated lead optimization by 6 months.
6. Technical Consultation
For material specifications, bulk pricing, or custom synthesis requirements:
Email: info@vivalr.com
Tel: (86) 15866781826
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