Taxifolin (CAS 480-18-2) Comprehensive Product Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Functional Benefits
- 3. Comparative Analysis of Commercial Grades
- 4. Industry Use Cases
- 5. Verified Client Implementations
- 6. Technical Consultation & Quotation
1. Product Overview & Specifications
Chemical Name: Taxifolin (Dihydroquercetin)
CAS: 480-18-2
Molecular Formula: C15H12O7
Molecular Weight: 304.25 g/mol
Appearance: Pale yellow crystalline powder
Solubility: Soluble in ethanol, acetone; slightly soluble in cold water
Melting Point: 230-233°C (dec.)
Storage: 2-8°C in airtight container
2. Key Applications & Functional Benefits
Core Applications:
- Pharmaceutical intermediates for anticancer drug development
- Natural antioxidant in functional foods and dietary supplements
- Anti-inflammatory agent in cosmeceutical formulations
- Antimicrobial additive in food preservation systems
Mechanisms of Action:
| Property | Mechanism | Efficacy Range |
|---|---|---|
| Antioxidant | Scavenges ROS/RNS through redox cycling | IC50: 193.3 μM (collagenase inhibition) |
| Anticancer | Induces apoptosis in P388 leukemia cells | 37-40% life extension at 100-150mg/kg |
| Antimicrobial | Disrupts bacterial cell membrane integrity | Effective against S. aureus & E. coli |
3. Comparative Analysis of Commercial Grades
| Parameter | Food Grade (98%) | Pharma Grade (99%) | Research Grade (HPLC) |
|---|---|---|---|
| Purity | >98% | >99% | >99.5% |
| Residual Solvents | <0.5% | <0.1% | <0.01% |
| Heavy Metals | <10ppm | <5ppm | <2ppm |
| Certifications | ISO 22000 | cGMP | USP/EP |
4. Industry Use Cases
Case 1: Nutraceutical Development
Enhanced bioavailability in combination with arabinogalactan for immune support supplements, demonstrating 30% improved absorption vs standalone quercetin.
Case 2: Cosmetic Preservation
0.5% concentration in skincare formulations extended product shelf-life by 40% while maintaining >99% microbial control.
5. Verified Client Implementations
Client A: Biopharmaceutical Innovator
Application: Leukemia treatment adjuvant
Outcome: Achieved 150mg/kg therapeutic window with 95% batch consistency
Client B: Functional Food Producer
Application: Natural preservative system
Result: 25% reduction in synthetic additives while meeting USDA organic standards
6. Technical Consultation & Quotation
Request product specifications or discuss custom synthesis:
Email: info@vivalr.com
Phone: (86) 15866781826
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