2-Amino-5-bromopyridine cas 1072-97-5

Chemical Name: 2-Amino-5-bromopyridine
CAS No.: 1072-97-5
Appearance: White crystalline solid powder
Assay:≥99.0

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Table of Contents

2-Amino-5-bromopyridine (CAS 1072-97-5)

Basic Specifications

Parameter Value
CAS Number 1072-97-5
Molecular Formula C5H5BrN2
Molecular Weight 173.01 g/mol
Appearance White to light yellow crystalline powder
Purity ≥98% (HPLC)
Melting Point 88-92°C
Storage 2-8°C in airtight container

Comparative Analysis

vs. Similar Bromopyridine Derivatives

Compound CAS Reactivity Price/kg Applications
2-Amino-5-bromopyridine 1072-97-5 High $420 Pharmaceutical intermediates
3-Bromo-2-aminopyridine 39856-58-1 Medium $380 Agrochemical synthesis
5-Bromo-2-aminopyridine 36953-37-4 Low $350 Material science

Industrial Applications

Pharmaceutical Intermediate

Critical component in antitumor drug synthesis, particularly for kinase inhibitors targeting EGFR and HER2 receptors.

Agrochemical Production

Key building block for neonicotinoid insecticides and fungicide precursors.

Coordination Chemistry

Ligand in transition metal complexes for catalytic applications and OLED material development.

Implementation Scenarios

Case 1: Anticancer Drug Synthesis

Used in 7-step synthesis of Erlotinib analogs, achieving 62% overall yield with 99.5% chiral purity.

Case 2: Cross-Coupling Reactions

Buchwald-Hartwig amination catalyst in API production, reducing reaction time from 24h to 8h.

Verified Client Implementations

PharmaHealth Solutions

Annual consumption: 850kg. Achieved 30% cost reduction in Lapatinib intermediate production through optimized bromination.

AgroGuard Technologies

Developed next-generation insecticide with 40% improved field efficacy using 1072-97-5 as core structure.

MaterialScience Inc.

Created copper(I) complexes with 2.8x enhanced luminescence efficiency for flexible displays.

Contact for Technical Consultation

Email: info@vivalr.com
Tel: (86) 15866781826

Request free samples or MSDS documentation:

  • Custom synthesis available
  • GMP-grade batches upon request
  • Technical support for process optimization
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