Chemical Name: 2-Amino-5-bromopyridine
CAS No.: 1072-97-5
Appearance: White crystalline solid powder
Assay:≥99.0
Parameter | Value |
---|---|
CAS Number | 1072-97-5 |
Molecular Formula | C5H5BrN2 |
Molecular Weight | 173.01 g/mol |
Appearance | White to light yellow crystalline powder |
Purity | ≥98% (HPLC) |
Melting Point | 88-92°C |
Storage | 2-8°C in airtight container |
Compound | CAS | Reactivity | Price/kg | Applications |
---|---|---|---|---|
2-Amino-5-bromopyridine | 1072-97-5 | High | $420 | Pharmaceutical intermediates |
3-Bromo-2-aminopyridine | 39856-58-1 | Medium | $380 | Agrochemical synthesis |
5-Bromo-2-aminopyridine | 36953-37-4 | Low | $350 | Material science |
Critical component in antitumor drug synthesis, particularly for kinase inhibitors targeting EGFR and HER2 receptors.
Key building block for neonicotinoid insecticides and fungicide precursors.
Ligand in transition metal complexes for catalytic applications and OLED material development.
Used in 7-step synthesis of Erlotinib analogs, achieving 62% overall yield with 99.5% chiral purity.
Buchwald-Hartwig amination catalyst in API production, reducing reaction time from 24h to 8h.
Annual consumption: 850kg. Achieved 30% cost reduction in Lapatinib intermediate production through optimized bromination.
Developed next-generation insecticide with 40% improved field efficacy using 1072-97-5 as core structure.
Created copper(I) complexes with 2.8x enhanced luminescence efficiency for flexible displays.
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