Bis(Pentafluorophenyl) Carbonate (CAS 59483-84-0): Technical Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 59483-84-0 |
| Molecular Formula | C13F10O3 |
| Molecular Weight | 394.12 g/mol |
| Appearance | White crystalline powder |
| Melting Point | 47-50°C |
| Density | 1.782 g/cm³ |
| Refractive Index | 1.447 |
2. Key Applications
- Oligonucleotide Synthesis: Critical reagent in phosphoramidite chemistry for DNA/RNA synthesis
- Peptide Coupling: Activates carboxyl groups for amide bond formation in nitrogenous peptides
- Derivatization Agent: Converts carboxylic acids to pentafluorophenyl esters for enhanced reactivity
- Polymer Chemistry: Building block for specialty fluoropolymers with high thermal stability
3. Operational Guidelines
Storage Conditions
- Store at 2-8°C in airtight containers
- Protect from moisture and light exposure
Safety Profile
- Non-hazardous per GHS classification
- Use standard lab PPE (gloves, goggles)
4. Industry Use Cases
| Industry | Application |
|---|---|
| Pharmaceuticals | Antisense oligonucleotide drug development |
| Biotechnology | siRNA therapeutic production |
| Materials Science | Fluorinated polymer synthesis |
5. Client Success Stories
Case Study 1: Nucleotide Research Institute
- Application: Large-scale oligonucleotide synthesis
- Result: Achieved 98% coupling efficiency
Case Study 2: Polymer Solutions Ltd.
- Application: High-performance fluoropolymer production
- Result: Developed materials with 300°C thermal stability
6. Contact for Technical Consultation
For pricing, technical specifications, or custom synthesis requirements:
| info@vivalr.com | |
| Phone | (86) 15866781826 |
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