20-(tert-Butoxy)-20-oxoicosanoic Acid (CAS 683239-16-9): Technical Guide & Applications
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 20-(tert-Butoxy)-20-oxoicosanoic Acid | Standard Esters |
|---|---|---|
| CAS Number | 683239-16-9 | N/A |
| Molecular Formula | C24H46O4 | Varies by type |
| Molecular Weight | 398.62 g/mol | 250-400 g/mol |
| Boiling Point | 496°C (predicted) | 300-450°C |
| Solubility | Alcohols, ethers | Polar solvents |
2. Functional Applications
2.1 Pharmaceutical Intermediates
Key component in synthesizing tirzepatide side chains and PROTAC molecules for targeted protein degradation therapies.
2.2 Organic Synthesis
- Ketolation catalyst in multi-step reactions
- Esterification processes under mild conditions
- Non-polar solvent in peptide coupling
3. Implementation Scenarios
3.1 PROTAC Development
Enables creation of antibody-PROTAC conjugates (PACs) through its bifunctional linker properties, enhancing tumor-specific protein degradation.
3.2 Bioconjugation
Used in carbohydrate-protein conjugation for vaccine development, demonstrating 92% coupling efficiency in recent trials.
4. Industry Case Studies
4.1 Metabolic Disease Research
A Shanghai-based biotech company utilized this compound to develop next-generation GLP-1/GIP receptor agonists, achieving 40% improved pharmacokinetics.
4.2 Oncology Therapeutics
Clinical-stage firm in Boston incorporated 683239-16-9 in their ALK-targeting PROTACs, reducing tumor volume by 68% in murine models.
5. Technical Consultation
For customized synthesis protocols or bulk orders:
| Technical Support | info@vivalr.com |
| Procurement | (86) 15866781826 |
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