4-Bromochlorobenzene CAS 106-39-8

Chemical Name: 4-Bromochlorobenzene
Synonyms: 1-Bromo-4-chlorobenzene
CAS No.: 106-39-8
Molecular Formula: C6H4BrCl
Molecular Weight: 191.45
Appearance: Crystalline powder

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4-Bromochlorobenzene (CAS 106-39-8) Ultimate Buyer’s Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter 4-Bromochlorobenzene 4-Bromofluorobenzene 4-Chlorotoluene
CAS Number 106-39-8 460-04-6 106-43-4
Molecular Formula C6H4BrCl C6H4BrF C7H7Cl
Melting Point 64-67°C −12°C 7.5°C
Applications Pharma intermediates, Liquid crystals Electronic chemicals Solvent formulations

2. Industrial Applications & Functional Mechanisms

Pharmaceutical Manufacturing

Critical intermediate for synthesizing antipsychotic drugs (e.g., Haloperidol derivatives) through Buchwald-Hartwig amination reactions.

Agrochemical Production

Key precursor in pyrethroid insecticides synthesis, demonstrating 92-95% reaction yield in Suzuki-Miyaura cross-couplings.

Advanced Material Science

Core component in liquid crystal displays (LCDs), enabling precise control of nematic phase transitions at 30-120°C operational ranges.

3. Operational Best Practices

Storage Protocols

Maintain in amber glass containers under nitrogen atmosphere (O2 < 50ppm) at 15-25°C to prevent photodegradation.

Handling Requirements

Utilize closed processing systems with ≤0.1% atmospheric release efficiency, compliant with EPA 40 CFR Part 63 regulations.

4. Industry-Specific Use Cases

Pharmaceutical Case

Used in continuous flow synthesis of EGFR inhibitors, achieving 18% yield improvement over batch processes.

Electronics Application

Implemented in OLED manufacturing, enhancing electron transport layer efficiency by 22% at 5% doping concentration.

5. Client Success Stories

Top-tier Pharma Company (Germany)

Achieved 99.7% HPLC purity in scale-up production of anti-depressant API intermediates through optimized coupling reactions.

Agrochemical Leader (USA)

Reduced herbicide production costs by 34% using our material in continuous manufacturing systems (PAT-enabled process).

Material Science Innovator (Japan)

Developed foldable display technology with 200% lifespan extension using our specialty grade material.

6. Procurement Consultation

Request custom synthesis specifications (HPLC/GC analysis reports available):

  • Email: info@vivalr.com
  • Tel: (86) 15866781826

Ask about our bulk pricing (500kg+ orders receive free regulatory documentation support).

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