4-(Trifluoromethylthio)benzoyl Chloride Cas 330-14-3

Chemical Name: 4-(Trifluoromethylthio)benzoyl chloride; 4-(Trifluoromethylthio)benzoic Chloride
CAS No.: 330-14-3
Molecular Fomula: C8H4ClF3OS
Molecular weight: 240.63
Appearance: Transparent liquid

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4-(Trifluoromethylthio)benzoyl Chloride (CAS 330-14-3) Comprehensive Guide

Table of Contents

1. Product Overview & Technical Specifications

Parameter Specification
CAS Number 330-14-3
Molecular Formula C8H4ClF3OS
Appearance Clear liquid
Density 1.445 g/mL at 25°C
Boiling Point 229-230°C
Refractive Index n20/D 1.5220
Flash Point 117°F (47.2°C)
HS Code 29309090.90

2. Key Applications & Industrial Uses

This specialty chemical serves as critical intermediate in:

  • Pharmaceutical synthesis (API production)
  • Agrochemical manufacturing
  • Advanced material development
  • Organic electronic components

3. Performance Comparison Analysis

Compound Reactivity Thermal Stability Solubility
4-(Trifluoromethylthio)benzoyl Chloride High Excellent Chlorinated solvents
Conventional Benzoyl Chlorides Moderate Good Polar aprotic solvents

4. Operational Best Practices

  • Store under inert gas atmosphere at 2-8°C
  • Use corrosion-resistant equipment (Hastelloy/glass-lined)
  • Maintain vapor pressure below 0.1 mmHg during processing

5. Industry Application Scenarios

Case 1: Pharmaceutical Intermediate Synthesis

Used in production of tyrosine kinase inhibitors through nucleophilic acyl substitution reactions.

Case 2: Liquid Crystal Material Development

Enables creation of fluorinated mesogens with enhanced dielectric anisotropy.

6. Client Success Stories

Chemical Manufacturer A (Guangdong, China)

Achieved 23% yield improvement in antidepressant API synthesis through optimized reaction protocols.

Research Institute B (California, USA)

Developed novel OLED materials with 15% enhanced luminance efficiency using this compound.

7. Expert Consultation

Contact our technical team for:

  • Custom synthesis protocols
  • Regulatory compliance guidance
  • Bulk order specifications

Email: info@vivalr.com
Phone: (86) 15866781826

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