1. Product Overview & Specifications

CAS No.: 820959-17-9
Molecular Formula: C₂₀H₂₈N₈O₇
Molecular Weight: 492.49 g/mol
Synonyms: Eyeseryl, Depuffin, Ac-βAla-His-Ser-His-OH

Key Parameters

2. Key Applications

• Anti-Edema Formulations: Reduces periorbital puffiness by inhibiting angiotensin-converting enzyme (ACE-1) and improving microcirculation.
• Anti-Aging Skincare: Enhances skin elasticity through glycation inhibition and SOD activity enhancement.
• Ocular Care Products: Clinically proven to diminish dark circles and under-eye bags in professional-grade eye creams.

3. Mechanism of Action

• Inhibits ACE-1 to regulate vascular pressure and reduce capillary leakage
• Blocks advanced glycation end-products (AGEs) formation via anti-glycation activity
• Enhances superoxide dismutase (SOD) activity for antioxidant protection

4. Usage Guidelines

Recommended Dosage: 0.005–0.05% in final formulations
Compatibility: Stable in pH 5–7 systems; add at final production stage
Formulation Types: Gels, serums, eye contour creams, anti-aging masks

5. Industry Use Cases

Case 1: Premium Eye Cream Development

A European skincare brand incorporated 0.03% Acetyl Tetrapeptide-5 into their award-winning eye cream, achieving 37% reduction in puffiness (4-week clinical trial).

Case 2: Professional Anti-Aging Line

A US cosmeceutical company utilized this peptide in their neck firming serum, demonstrating 29% improvement in skin elasticity metrics.

6. Contact for Technical Inquiry

For formulation support, bulk pricing, or clinical data:
Email: info@vivalr.com
Tel: (86) 15866781826