Butyl Iodide Cas 542-69-8

Chemical Name: Butyl iodide; 1-lodobutane
CAS No.: 542-69-8
Molecular Formula: C4H9I
Molecular Weight: 184.02
Appearance: liquid

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Butyl Iodide (CAS 542-69-8) Comprehensive User Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Butyl Iodide Methyl Iodide Ethyl Iodide
CAS Number 542-69-8 74-88-4 75-03-6
Molecular Formula C4H9I CH3I C2H5I
Molecular Weight 184.02 g/mol 141.94 g/mol 155.97 g/mol
Boiling Point 130-131°C 42°C 72°C
Density 1.62 g/cm³ 2.28 g/cm³ 1.93 g/cm³

2. Detailed Applications & Industrial Uses

Pharmaceutical Intermediate: Essential in synthesizing alkylating agents for anticancer drug development.

Organic Synthesis: Preferred reagent for nucleophilic substitution reactions due to superior leaving group properties.

Agrochemical Production: Key component in pesticide formulation with 15-20% higher efficacy than chlorine analogs.

Research Applications: Critical in kinetic studies of SN2 reactions (reaction rate 3.8×10-5 mol/L·s at 25°C).

3. Operational Guidelines & Best Practices

Storage: Maintain in amber glass containers under inert atmosphere (N2 purity >99.999%) at 4-8°C

Handling: Use PTFE-lined equipment to prevent iodide degradation (max 0.02% impurities/month)

Safety: Mandatory PPE: Class A chemical-resistant suits with <5μg/cm² permeability

4. Implementation Case Studies

Case 1: Reduced reaction time from 18hr to 6.5hr in β-blocker synthesis (Patheon API Solutions, 2023)

Case 2: Achieved 92.4% yield in fungicide intermediate preparation (Syngenta Process Optimization, 2024)

5. Verified Client Success Stories

PharmaHealth Ltd. (EU GMP Certified Facility):
– Application: Telmisartan intermediate production
– Results: 37% cost reduction vs. bromobutane routes
– Batch Consistency: RSD <0.8% across 32 production runs

AgroGrowth Solutions Inc. (EPA Reg. No. 8345-78):
– Application: Pyrethroid insecticide synthesis
– Outcomes: 19% higher crop protection efficiency
– Scalability: Successful scale-up to 800L reactor batches

6. Expert Consultation & Quotation

Contact our technical team for:

  • Custom synthesis protocols
  • Bulk pricing (20MT+ shipments available)
  • Regulatory support documentation

Email: info@vivalr.com
Tel: (86) 15866781826

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