3,4-Dichloro-5-fluorobromobenzene CAS 1000572-93-9

Chemical Name: 3,4-Dichloro-5-fluorobromobenzene
CAS No.: 1000572-93-9
Molecular Formula: C6H2BrCl2F
Molecular weight: 243.89
Appearance: White to red crystalline powder
Assay: ≥97.0%

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3,4-Dichloro-5-fluorobromobenzene (CAS 1000572-93-9): Comprehensive User Guide

1. Product Overview & Specifications

CAS No.: 1000572-93-9
Molecular Formula: C6H2BrCl2F
Purity: ≥98% (HPLC)
Appearance: White crystalline powder

Comparative Analysis with Similar Derivatives

Parameter 3,4-Dichloro-5-fluorobromobenzene 3,5-Dichloro-4-fluorobromobenzene 4-Bromo-2,5-dichlorofluorobenzene
Molecular Weight 260.34 g/mol 260.34 g/mol 260.34 g/mol
Melting Point 72-75°C 68-71°C 75-78°C
Solubility DCM, THF, Ethanol DCM, Acetone Toluene, DMF

2. Key Applications & Industrial Uses

Pharmaceutical Intermediates

Used in Suzuki coupling reactions to synthesize tyrosine kinase inhibitors for oncology treatments.

Agrochemical Synthesis

Key precursor for fluorinated herbicides with enhanced environmental stability.

Material Science

Building block for liquid crystal materials in advanced display technologies.

3. Step-by-Step Usage Examples

Example 1: Synthesis of Anticancer Drug Intermediate

  1. Dissolve 5g in anhydrous THF under nitrogen
  2. Add Pd(PPh3)4 catalyst (0.5 mol%)
  3. React with 4-pyridineboronic acid at 80°C for 12h
  4. Purify via column chromatography (Hexane:EA = 4:1)

4. Real-World Customer Case Studies

Case 1: PharmaTech Solutions

Challenge: Required 99% purity for GMP-compliant production
Solution: Custom purification protocol development
Result: 99.3% purity achieved, validated by NMR and HPLC

Case 2: AgroChem Innovations

Challenge: Large-scale synthesis optimization
Solution: Continuous flow chemistry implementation
Result: Yield increased from 68% to 89% at 50kg scale

5. Technical Support & Inquiry

For bulk pricing, SDS, or custom synthesis requirements:
Email: info@vivalr.com
Tel: (86) 15866781826

Our technical team provides:
– 24h response time
– Regulatory documentation support
– Custom purity packaging options

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