Ribonuclease A CAS 9001-99-4

Chemical Name: Ribonuclease A
Synonyms: Alkaline ribonuclease; Amphinase; Pancreatic ribonuclease; RNase; Ribonuclease; Ribonucleic phosphatase; S-RNase
CAS No.: 9001-99-4
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Ribonuclease A (CAS 9001-99-4) Product Guide

1. Product Specifications & Comparative Analysis

Parameter RNase A (CAS 9001-99-4) Alternative Enzymes
Molecular Weight 13.7 kDa Varies by source (15-18 kDa)
Optimal pH 7.0-8.0 6.5-7.5 for most competitors
Thermal Stability Retains 90% activity at 60°C Typically 50-70°C range

2. Detailed Applications in Life Sciences

Primary research applications include:

  • RNA purification workflows
  • Chromosomal DNA isolation protocols
  • Viral RNA elimination in vaccine production

3. Operational Guidelines & Protocol Optimization

Standard concentration: 10 µg/mL in TE buffer (pH 7.5). Heat inactivation recommended at 65°C for 15 minutes post-digestion.

4. Industry Application Case Studies

4.1 mRNA Vaccine Production

Used in plasmid DNA purification for COVID-19 vaccine development, achieving 99.8% host RNA clearance.

4.2 Cancer Genomics Research

Implemented in single-cell RNA sequencing workflows at Stanford Medical Center.

5. Verified Client Implementations

5.1 BioTech Innovations Inc. (2023)

Application: NGS library preparation
Outcome: Reduced rRNA contamination by 82%

5.2 PharmaCore Solutions (2022)

Application: Therapeutic protein expression
Result: Increased plasmid purity by 3.2-fold

6. Technical Consultation & Ordering

Contact our RNA specialists:
Email: info@vivalr.com
Tel: (86) 15866781826

Request batch-specific COA or MSDS documentation.

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