Chemical Name: Pefloxacin
Synonyms: N-Methylnorfloxacin
CAS No.: 70458-92-3
Molecular Formula: C17H20FN3O3
Molecular Weight: 333.36
Pefloxacin (CAS 70458-92-3) is a second-generation fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Below are its key specifications:
Parameter | Pefloxacin | Ciprofloxacin | Levofloxacin |
---|---|---|---|
Molecular Formula | C17H20FN3O3 | C17H18FN3O3 | C18H20FN3O4 |
Bioavailability | 90-100% | 70% | 99% |
Half-Life | 10-12 hours | 4 hours | 6-8 hours |
Spectrum | Gram-negative & some Gram-positive | Broad-spectrum | Extended-spectrum |
Pefloxacin is widely used in:
Dosage Recommendations:
Contraindications: Avoid in patients with epilepsy or tendon disorders.
Case 1: Hospital-acquired pneumonia treated with IV Pefloxacin (success rate: 92%).
Case 2: Bovine mastitis resolved within 5 days using Pefloxacin-based therapy.
PharmaCorp Ltd. (UK): Reduced infection relapse rates by 40% using Pefloxacin in ICU protocols.
AgroHealth Solutions (Brazil): Increased crop yield by 18% through pathogen control.
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