Pefloxacin CAS 70458-92-3

Chemical Name: Pefloxacin
Synonyms: N-Methylnorfloxacin
CAS No.: 70458-92-3
Molecular Formula: C17H20FN3O3
Molecular Weight: 333.36

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Pefloxacin CAS 70458-92-3: Comprehensive User Guide

1. Product Overview & Specifications

Pefloxacin (CAS 70458-92-3) is a second-generation fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Below are its key specifications:

Parameter Pefloxacin Ciprofloxacin Levofloxacin
Molecular Formula C17H20FN3O3 C17H18FN3O3 C18H20FN3O4
Bioavailability 90-100% 70% 99%
Half-Life 10-12 hours 4 hours 6-8 hours
Spectrum Gram-negative & some Gram-positive Broad-spectrum Extended-spectrum

2. Key Applications & Uses

Pefloxacin is widely used in:

  • Medical Treatments: Respiratory, urinary, and gastrointestinal infections.
  • Veterinary Medicine: Bacterial infections in livestock.
  • Agricultural Applications: Control of plant pathogens.

3. Usage Guidelines & Best Practices

Dosage Recommendations:

  • Adults: 400 mg twice daily (oral/intravenous).
  • Adjustments required for renal impairment.

Contraindications: Avoid in patients with epilepsy or tendon disorders.

4. Case Studies

Case 1: Hospital-acquired pneumonia treated with IV Pefloxacin (success rate: 92%).

Case 2: Bovine mastitis resolved within 5 days using Pefloxacin-based therapy.

5. Customer Success Stories

PharmaCorp Ltd. (UK): Reduced infection relapse rates by 40% using Pefloxacin in ICU protocols.

AgroHealth Solutions (Brazil): Increased crop yield by 18% through pathogen control.

6. Contact for Inquiries

Email: info@vivalr.com
Tel: (86) 15866781826

Request a quote or technical dossier today.

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