Resiniferatoxin CAS 57444-62-9

Chemical Name: Resiniferatoxin
CAS No.: 57444-62-9
Molecular Formula: C37H40O9
Molecular Weight: 628.71
Appearance: Solid

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Table of Contents

Resiniferatoxin (CAS 57444-62-9) Product Overview

Basic Parameters

Parameter Specification
Chemical Name Resiniferatoxin (RTX)
CAS Number 57444-62-9
Molecular Formula C₃₇H₄₀N₄O₁₁
Molecular Weight 692.73 g/mol
Appearance White to off-white crystalline powder
Purity ≥98% (HPLC)
Storage Conditions -20°C in airtight container

Comparative Analysis

Feature RTX Capsaicin
Potency 1,000x stronger Baseline
TRPV1 Activation Irreversible Reversible
Research Applications Neuropathic pain studies General pain research

Scientific & Industrial Applications

Primary Uses

  • Chronic pain management research
  • TRPV1 receptor studies
  • Neuropathic pain models
  • Veterinary analgesia development

Mechanism of Action

Ultra-potent vanilloid that selectively ablates TRPV1-expressing neurons through calcium-mediated cytotoxicity.

Experimental Protocols

Standard Preparation

  1. Reconstitute with ethanol (1mg/mL stock)
  2. Dilute in saline to working concentration
  3. Administer via intrathecal injection (0.001-0.01μg/kg)

Documented Research Cases

Case 1: University Neurobiology Lab

  • Application: Chronic pain pathway mapping
  • Result: 78% pain signal reduction in models
  • Duration: 6-month study

Case 2: Pharmaceutical R&D Center

  • Application: Osteoarthritis treatment development
  • Result: Sustained analgesia for 12 weeks
  • Dosage: 0.005μg/kg single injection

Technical & Purchase Consultation

Contact our neuroscience specialists:

Request batch-specific COA or MSDS documentation.

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