Trimethylamine (CAS 75-50-3): Comprehensive Technical Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Trimethylamine | Alternative Amines |
|---|---|---|
| CAS Number | 75-50-3 | Varies by compound |
| Molecular Formula | C3H9N | Typically CnH2n+3N |
| Physical State | Colorless gas (liquefied under pressure) | Liquid/Solid variants |
| Flash Point | -6.67°C (closed cup) | Higher in most analogues |
| Explosive Limits | 2.0%-11.6% (in air) | Narrower ranges typical |
2. Industrial & Commercial Applications
Core Functional Domains:
- Chemical Synthesis: Primary catalyst in quaternary ammonium compound production
- Polymer Industry: Key precursor for ion-exchange resins and surface-active agents
- Pharmaceuticals: Intermediate in antibiotic synthesis and disinfectant formulations
- Agriculture: Active component in herbicides and plant growth regulators
- Advanced Materials: Functional group in PEG-based biomaterials (e.g., TMA-PEG-TMA)
3. Functional Mechanisms
Operational Characteristics:
- Nucleophilic agent in SN2 reactions
- Proton acceptor in acid-base catalysis (pKb 4.63)
- Coordination center in metal complex formations
- Charge carrier in electrochemical applications
4. Implementation Case Studies
Typical Operational Scenarios:
| Application | Concentration | Process Parameters |
|---|---|---|
| Surfactant Production | 15-25% aqueous solution | 60-80°C, pH 8.5-9.5 |
| Drug Intermediate Synthesis | Anhydrous grade | N2 atmosphere, -20°C storage |
| Wastewater Treatment | 0.1-0.5% additive | Continuous flow systems |
5. Client Success Stories
Xi’an Kaison Biological Technology:
- Application: mPEG-TMA synthesis for drug delivery systems
- Result: 40% improvement in nanoparticle stability
- Molecular Weight: Customized 5k-20k Da PEG chains
Wuhan Xinsheng Jiali Biotech:
- Application: Trimethylamine borane complex production
- Output: 98.5% purity pharmaceutical intermediates
- Scale: 500kg/month production capacity
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