Dimethyl Furan-2,5-dicarboxylate CAS 4282-32-0: Comprehensive User Guide

1. Product Overview & Specifications

Dimethyl Furan-2,5-dicarboxylate (CAS 4282-32-0) is a high-purity ester derivative of furan dicarboxylic acid, widely used as a key intermediate in advanced polymer synthesis and pharmaceutical manufacturing.

2. Key Applications & Use Cases

2.1 Pharmaceutical Intermediate

Used in synthesis of antiviral agents and oncology drugs requiring high structural precision.

2.2 Bio-based Polymers

Critical monomer for producing polyethylene furoate (PEF) with 20% better barrier properties than PET.

2.3 Specialty Chemicals

Essential for creating UV-resistant coatings and high-performance adhesives.

3. Step-by-Step Usage Examples

3.1 Polymer Synthesis Protocol

1. Charge reactor with 1 mol dimethyl furan-2,5-dicarboxylate
2. Add 1.05 mol ethylene glycol at 60°C
3. Catalyze with 0.01% titanium(IV) butoxide
4. Polymerize at 220°C under vacuum

3.2 Pharmaceutical Intermediate Preparation

1. React with hydrazine hydrate in ethanol
2. Stir at reflux for 6 hours
3. Crystallize product at -20°C

4. Real Client Success Stories

Case 1: Leading Bioplastics Manufacturer

Challenge: Develop food-grade PEF with <2% residual monomers
Solution: Optimized esterification using our 99.8% purity grade
Result: Achieved 1.3% residuals with 30% faster polymerization

Case 2: Top-10 Pharma Company

Challenge: Scale up antiviral drug intermediate
Solution: Custom particle size distribution (50-75μm)
Result: Increased batch yield from 78% to 92%

5. Request Customized Solutions

Our technical team specializes in developing application-specific grades:
➤ Pharmaceutical API-grade (ICH Q7 compliant)
➤ Polymerization-grade (≤10 ppm metal content)
➤ Custom ester derivatives

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