Trimethylphloroglucinol (CAS 4463-03-0): Comprehensive User Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Trimethylphloroglucinol | Standard Phloroglucinol | Trimethyl Derivatives |
|---|---|---|---|
| CAS Number | 4463-03-0 | 108-73-6 | Varies |
| Purity Grade | ≥99% (HPLC) | ≥97% | 90-98% |
| Melting Point | 160-165°C | 217-220°C | 155-170°C |
| Solubility (25°C) | Ethanol: 50 mg/mL DMSO: 100 mg/mL |
Water: 10 mg/mL | Limited solubility |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediate
Critical precursor in synthesis of:
- Anticancer drug candidates
- Antioxidant formulations
- Neuroprotective agents
Advanced Material Science
- Coordination polymer development
- Metal-organic frameworks (MOFs)
- Photocatalytic compounds
3. Step-by-Step Usage Protocols
Laboratory-scale Synthesis (Example)
- Weigh 500mg ±5mg under inert atmosphere
- Dissolve in anhydrous DMSO (10mL/mg)
- Maintain reaction at 40°C ±2°C for 2hrs
- Purify via column chromatography (hexane/EA 3:1)
4. Verified Client Success Stories
Case 1: European Pharma Innovator
| Challenge | Low yield (38%) in kinase inhibitor synthesis |
|---|---|
| Solution | Optimized Trimethylphloroglucinol stoichiometry (1:1.2 molar ratio) |
| Result | 82% yield improvement | 18-month patent advantage |
Case 2: Asian Material Research Consortium
| Objective | Develop UV-stable polymer coatings |
|---|---|
| Implementation | 0.5% w/w additive in PMMA matrix |
| Outcome | 400% UV resistance enhancement | ASTM G154 compliant |
5. Request Customized Solutions
Our technical team specializes in:
- Bulk synthesis (100kg+ batches)
- GMP-grade production
- Application-specific formulation
Contact our chemistry experts:
Email: info@vivalr.com
Tel: (86) 15866781826
Technical Support: 72-hour response guarantee for all technical queries
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