L-Proline (CAS 147-85-3): Comprehensive Technical Guide
Table of Contents
1. Key Specifications & Comparative Analysis
| Parameter | L-Proline | Standard Amino Acids |
|---|---|---|
| CAS Number | 147-85-3 | Varies |
| Molecular Formula | C5H9NO2 | Typically CnH2n+1NO2 |
| Molecular Weight | 115.13 g/mol | 75-204 g/mol |
| Melting Point | 228°C (dec.) | 200-300°C |
| Solubility | 154.56g/100ml H2O (20°C) | Variable water solubility |
| Isoelectric Point | 6.3 | 5.5-6.5 |
2. Industrial & Scientific Applications
Pharmaceutical Manufacturing
- Primary intermediate for ACE inhibitors: Captopril, Enalapril (anti-hypertensives)
- Essential component in parenteral nutrition formulations
- Precursor for novel cardioprotective agents
Food Technology
- Flavor enhancer in Maillard reaction products
- Nutritional additive in sports supplements
- Stabilizer in processed food matrices
Biochemical Research
- Critical component in cell culture media
- Substrate for enzymatic activity studies
- Chiral synthon in asymmetric synthesis
3. Implementation Case Studies
Pharmaceutical Synthesis Optimization
A European API manufacturer achieved 23% yield improvement in Enalapril production through optimized L-Proline crystallization protocols, reducing production costs by €1.2M annually.
Neuroscience Research Breakthrough
Preclinical studies demonstrate 40% reduction in ASD-like behaviors in murine models through dietary L-Proline supplementation (5% w/v in drinking water), showing significant microbiome modulation.
4. Client Success Stories
Major Nutraceutical Producer
Integrated L-Proline into recovery supplements, achieving 18% faster muscle regeneration metrics in clinical trials (n=450 subjects).
Biopharmaceutical Innovator
Developed sustained-release cardioprotective formulation using L-Proline co-crystals, extending therapeutic window by 6.5 hours.
5. Technical Consultation
For formulation support or bulk procurement:
Email: info@vivalr.com
Tel: (86) 15866781826
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