4-Fluoroanisole (CAS 459-60-9): Comprehensive Technical Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 4-Fluoroanisole | Industry Benchmark |
|---|---|---|
| CAS Number | 459-60-9 | N/A |
| Molecular Formula | C7H7FO | N/A |
| Purity | ≥99% (Pharma Grade) | ≥97% (Industrial Grade) |
| Melting Point | -45°C | -40°C to -50°C |
| Boiling Point | 157°C | 150-160°C |
| Density (25°C) | 1.114 g/mL | 1.10-1.15 g/mL |
| Refractive Index | 1.486-1.488 | 1.480-1.490 |
| HS Code | 2909309090 | 290930**** |
2. Key Applications & Industrial Uses
2.1 Pharmaceutical Intermediate
Essential for synthesizing fluorinated active pharmaceutical ingredients (APIs) in antidepressants and antipsychotics.
2.2 Agrochemical Production
Critical component in fluorinated pesticide formulations, enhancing bioactivity and environmental stability.
2.3 Liquid Crystal Materials
Core building block for advanced fluorinated liquid crystal compounds in display technologies.
2.4 Specialty Chemicals
Intermediate in production of fluorinated surfactants and high-performance polymers.
3. Operational Guidelines & Safety Protocols
3.1 Storage Requirements
- Temperature: 2-8°C in sealed containers
- Environment: Dry, inert atmosphere (N2 preferred)
- Shelf Life: 24 months under optimal conditions
3.2 Handling Precautions
- PPE Requirements: Chemical-resistant gloves, face shield, vapor respirator
- Ventilation: Use in fume hood with ≥100 fpm airflow
- Incompatibilities: Strong oxidizers, alkali metals
3.3 Emergency Procedures
- Fire: Use alcohol-resistant foam (AR-AFFF)
- Spill: Contain with inert absorbent (vermiculite preferred)
- Exposure: Immediate eye irrigation (15+ minutes), medical consultation required
4. Verified Client Implementations
Case Study 1: Pharmaceutical Manufacturer (East China)
- Application: Synthesis of fluorinated antidepressant intermediates
- Volume: 850 kg/month
- Purity Requirement: ≥99.5%
- Outcome: 18% yield improvement vs. previous synthesis route
Case Study 2: Advanced Materials Producer (Germany)
- Application: Liquid crystal material for 8K displays
- Technical Challenge: Low residual metal content (<5 ppm)
- Solution: Custom distillation process achieving ≤2 ppm metal content
Case Study 3: Agrochemical Formulator (Brazil)
- Application: Fluorinated systemic herbicide
- Result: 40% reduction in environmental persistence vs. non-fluorinated analogs
- Regulatory: Successfully met EU REACH compliance requirements
5. Commercial Inquiry & Technical Support
For pricing tiers, bulk orders (25kg+), or custom synthesis requirements:
| Contact Method | Details |
|---|---|
| Technical Support | +86 15866781826 (24/7 Emergency Line) |
| info@vivalr.com | |
| Lead Time | 3-5 business days (Standard Orders) 10-15 days (Custom Syntheses) |



评论
目前还没有评论。