Comprehensive Guide to 3-Fluoro-4-nitrobenzoic Acid (CAS 403-21-4)
Table of Contents
- 1. Product Overview & Specifications
- 2. Applications & Industrial Uses
- 3. Usage Scenarios & Case Studies
- 4. Client Success Stories
- 5. Technical Support & Inquiry
1. Product Overview & Specifications
3-Fluoro-4-nitrobenzoic Acid (CAS 403-21-4) is a fluorinated nitrobenzoic acid derivative widely used in pharmaceuticals, agrochemicals, and organic synthesis.
| Parameter | Specification | Comparison with 4-Nitrobenzoic Acid |
|---|---|---|
| Molecular Formula | C7H4FNO4 | Additional fluorine atom enhances reactivity |
| Molecular Weight | 185.11 g/mol | Higher molecular weight due to fluorine |
| Appearance | Light yellow crystalline powder | Similar to non-fluorinated analogs |
| Melting Point | 152-155°C | Lower than 4-nitrobenzoic acid (242°C) |
| Solubility | Soluble in DMSO, methanol; insoluble in water | Improved organic solvent compatibility |
2. Applications & Industrial Uses
Key Applications:
- Pharmaceutical intermediates for anticancer drugs
- Agrochemical precursors for herbicides
- Fluorine-containing polymer modifiers
- Cross-coupling reactions in organic synthesis
3. Usage Scenarios & Case Studies
Scenario 1: Synthesis of kinase inhibitors
Used as a building block in JAK2/STAT3 pathway inhibitors.
Scenario 2: Herbicide development
Key intermediate in fluorinated phenoxyherbicides.
4. Client Success Stories
Case Study 1: Swiss Pharma Innovator (2023)
– Requirement: 98.5% pure material for Phase II clinical trial compounds
– Solution: Customized purification process achieving 99.2% purity
– Outcome: Successful API synthesis with improved yield
Case Study 2: German Agrochemical Leader (2024)
– Challenge: Batch consistency in fluorination reactions
– Resolution: Optimized synthesis protocol with ≤0.3% variance
– Result: 15% cost reduction in final herbicide production
5. Technical Support & Inquiry
Contact our chemical experts for:
- Custom synthesis requirements
- Bulk pricing (1kg to ton-scale)
- Regulatory documentation support
Email: info@vivalr.com
Phone: (86) 15866781826
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