Table of Contents
- Product Overview
- Specifications & Parameter Comparison
- Key Applications
- Usage Guidelines
- Industry Case Studies
- Contact for Quotation
Methyltriphenylphosphonium Bromide (CAS 1779-49-3) Overview
A quaternary phosphonium salt widely used as a reagent in organic synthesis, particularly for Wittig reactions. White crystalline solid soluble in polar solvents like dichloromethane or DMF.
Basic Properties
| Parameter | Value |
|---|---|
| CAS Number | 1779-49-3 |
| Molecular Formula | C19H18BrP |
| Molecular Weight | 357.22 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Storage | 2-8°C in dry environment |
Technical Specifications Comparison
| Vendor | Purity | Packaging | Price (USD/kg) | MOQ |
|---|---|---|---|---|
| Sigma-Aldrich | 98% | 100g, 500g | $450-$2,100 | 100g |
| TCI Chemicals | 97% | 25g, 100g | $380-$1,800 | 25g |
| VIVALR | 99% | 1kg, 5kg | $320-$1,500 | 500g |
Industrial Applications
1. Wittig Reaction Catalyst
Converts aldehydes/ketones to alkenes through phosphorus ylide intermediates. Reaction conditions: 60-80°C in THF/DMF with strong base (e.g., KOtBu).
2. Phase Transfer Catalyst
Facilitates reactions between immiscible phases in:
– Pharmaceutical intermediates synthesis
– Polymer modification processes
3. Ionic Liquid Precursor
Used in electrolyte formulations for lithium-ion batteries and supercapacitors.
Operational Guidelines
Reaction Setup Example
| Component | Quantity |
|---|---|
| Methyltriphenylphosphonium bromide | 1.2 eq |
| Carbonyl compound | 1.0 eq |
| KOtBu | 2.0 eq |
| THF | 0.2M concentration |
Procedure: Add phosphonium salt and base under N2, stir at 65°C for 1hr before carbonyl addition.
Client Success Stories
Case 1: Pharma Intermediate Production
Client: Top 10 Global Pharmaceutical Company
Application: Synthesis of Tamoxifen precursor
Result: 92% yield improvement vs. traditional methods
Scale: 800kg/month production
Case 2: OLED Material Development
Client: Advanced Materials Research Lab
Application: Conjugated polymer side-chain modification
Result: Achieved 98.5% regioselectivity
Process: Continuous flow reaction at 5kg/batch
Request Customized Solution
Contact our technical team for:
– Bulk pricing (20kg+)
– GMP-grade material
– Custom synthesis services
Email: info@vivalr.com
Phone: (86) 15866781826



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