Methyltriphenylphosphonium bromide CAS 1779-49-3

Chemical Name: Methyltriphenylphosphonium bromide
CAS No.: 1779-49-3
Molecular Fomula: C19H18BrP
Molecular weight: 357.22
Appearance: White powder

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Table of Contents

Methyltriphenylphosphonium Bromide (CAS 1779-49-3) Overview

A quaternary phosphonium salt widely used as a reagent in organic synthesis, particularly for Wittig reactions. White crystalline solid soluble in polar solvents like dichloromethane or DMF.

Basic Properties

Parameter Value
CAS Number 1779-49-3
Molecular Formula C19H18BrP
Molecular Weight 357.22 g/mol
Appearance White to off-white crystalline powder
Purity ≥98% (HPLC)
Storage 2-8°C in dry environment

Technical Specifications Comparison

Vendor Purity Packaging Price (USD/kg) MOQ
Sigma-Aldrich 98% 100g, 500g $450-$2,100 100g
TCI Chemicals 97% 25g, 100g $380-$1,800 25g
VIVALR 99% 1kg, 5kg $320-$1,500 500g

Industrial Applications

1. Wittig Reaction Catalyst

Converts aldehydes/ketones to alkenes through phosphorus ylide intermediates. Reaction conditions: 60-80°C in THF/DMF with strong base (e.g., KOtBu).

2. Phase Transfer Catalyst

Facilitates reactions between immiscible phases in:
– Pharmaceutical intermediates synthesis
– Polymer modification processes

3. Ionic Liquid Precursor

Used in electrolyte formulations for lithium-ion batteries and supercapacitors.

Operational Guidelines

Reaction Setup Example

Component Quantity
Methyltriphenylphosphonium bromide 1.2 eq
Carbonyl compound 1.0 eq
KOtBu 2.0 eq
THF 0.2M concentration

Procedure: Add phosphonium salt and base under N2, stir at 65°C for 1hr before carbonyl addition.

Client Success Stories

Case 1: Pharma Intermediate Production

Client: Top 10 Global Pharmaceutical Company
Application: Synthesis of Tamoxifen precursor
Result: 92% yield improvement vs. traditional methods
Scale: 800kg/month production

Case 2: OLED Material Development

Client: Advanced Materials Research Lab
Application: Conjugated polymer side-chain modification
Result: Achieved 98.5% regioselectivity
Process: Continuous flow reaction at 5kg/batch

Request Customized Solution

Contact our technical team for:
– Bulk pricing (20kg+)
– GMP-grade material
– Custom synthesis services

Email: info@vivalr.com
Phone: (86) 15866781826

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