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1-Bromo-6-chloro-dibenzofuran CAS 2177301-52-7 Technical Guide
Table of Contents
- 1. Product Specifications & Comparative Analysis
- 2. Functional Applications
- 3. Operational Guidelines
- 4. Implementation Case Studies
- 5. Verified Client Applications
- 6. Commercial Inquiry Protocol
1. Product Specifications & Comparative Analysis
| Parameter | 1-Bromo-6-chloro-dibenzofuran | Analogous Compounds |
|---|---|---|
| CAS Number | 2177301-52-7 | N/A |
| Molecular Formula | C12H6BrClO | C12H7BrO (Mono-substituted) |
| Molecular Weight | 285.53 g/mol | 239.08 g/mol |
| Purity Grade | ≥98% (HPLC) | ≥95% (Standard) |
| Thermal Stability | Stable up to 250°C | 220°C (Decomposition) |
2. Functional Applications
This halogenated dibenzofuran derivative demonstrates exceptional performance in:
- Pharmaceutical intermediates for kinase inhibitors
- OLED material precursors
- Cross-coupling reactions (Suzuki, Buchwald-Hartwig)
- Liquid crystal material synthesis
- Polymer modification agents
3. Operational Guidelines
Handling Protocol:
- Storage: Nitrogen atmosphere at -20°C
- Solubility: 25mg/mL in DMF (heated to 60°C)
- Incompatible with strong oxidizers
4. Implementation Case Studies
Case A: Pharmaceutical Synthesis
Used as key intermediate in Bruton’s tyrosine kinase (BTK) inhibitor development, achieving 92% reaction yield under palladium catalysis.
5. Verified Client Applications
| Client | Industry | Application | Outcome |
|---|---|---|---|
| EuroPharma Solutions | Drug Development | JAK3 inhibitor synthesis | Reduced synthesis steps from 7 to 4 |
| MaterialSci Co.Ltd | Advanced Materials | Electron transport layer fabrication | 15% OLED efficiency improvement |
6. Commercial Inquiry Protocol
Contact our technical team for:
- Custom synthesis specifications
- Bulk pricing (25kg+ quantities)
- MSDS/TDS documentation
Email: info@vivalr.com
Tel: (86) 15866781826
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