3-Chloropropanesulfonyl Chloride Cas 1633-82-5

Chemical Name: 3-Chloropropanesulfonyl chloride
CAS No.: 1633-82-5
Molecular Fomula: C3H6Cl2O2S
Molecular weight: 177.03
Appearance: Clear colorless to light brown liquid
Assay: 98%min

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Table of Contents

Product Overview & Specifications

3-Chloropropanesulfonyl Chloride (CAS 1633-82-5)

Parameter Value
Molecular Formula C3H6Cl2O2S
Molecular Weight 177.05 g/mol
Boiling Point 70°C at 0.5 mmHg
Density 1.456 g/cm³
Refractive Index 1.489
EC Number 216-646-3
MDL Number MFCD00007463
Sensitivity Moisture-sensitive

Applications & Industrial Uses

Key Functional Roles

This sulfonyl chloride derivative serves as a critical intermediate in asymmetric synthesis under cinchona alkaloid catalysis. It enables the generation of chiral sulfonamides and sulfonate esters through reactions with imines and glyoxylic acid derivatives. Primary applications include:

  • Pharmaceutical intermediates for chiral drug synthesis
  • Agrochemical precursor development
  • Specialty chemical manufacturing

Operational Guidelines

Handling Protocols

  • Store under inert gas (N2 or Ar) at 2-8°C
  • Use moisture-free environments (glove box recommended)
  • Incompatible with strong bases and oxidizing agents

Case Studies

Pharmaceutical Intermediate Synthesis

A leading API manufacturer achieved 92% enantiomeric excess in sulfonamide production through optimized reaction conditions using this compound as key chiral auxiliary.

Client Success Stories

Shanghai Yubio Biotech

Implemented batch-scale production of antiviral drug intermediates with 15% yield improvement through our technical consultation services.

AMRESCO Research Solutions

Developed novel analytical reference standards using our GMP-grade material, reducing method development time by 40%.

Inquiry & Technical Support

For material specifications, MSDS, or custom synthesis requirements:

Email: info@vivalr.com
Tel: (86) 15866781826

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