Triethylene Glycol Dimethyl Ether CAS 112-49-2

Chemical Name: Triethylene Glycol Dimethyl Ether
Synonyms: 1,2-Bis(2-methoxyethoxy)ethane; Triglyme
CAS No.: 112-49-2
Molecular Formula: C8H18O4
Molecular Weight: 178.23
Appearance: Liquid

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Triethylene Glycol Dimethyl Ether (CAS 112-49-2): Comprehensive User Guide

1. Product Introduction & Specifications

Triethylene Glycol Dimethyl Ether (TEGDME, CAS 112-49-2) is a high-purity solvent with the molecular formula C8H18O4. Key parameters include:

Parameter TEGDME Ethylene Glycol Diethylene Glycol
Boiling Point (°C) 222-224 197 245
Flash Point (°C) 113 111 124
Viscosity (cP at 25°C) 3.5 16 30
Dielectric Constant 7.2 37.7 31.7

Advantages: Low toxicity, high thermal stability, and superior solvent power for electrolytes.

2. Key Applications

2.1 Lithium-Ion Battery Electrolytes

Used as a co-solvent in lithium salts (e.g., LiTFSI) for high-voltage batteries due to its wide electrochemical window (>4.5V).

2.2 Pharmaceutical Synthesis

Acts as a reaction medium for Grignard reactions and catalyst support in API manufacturing.

2.3 Industrial Coatings

Enhances flow properties in epoxy and polyurethane coatings while reducing VOC emissions.

3. Industrial Use Cases

Case 1: Battery Manufacturing

Formula: 1M LiPF6 in EC:TEGDME (3:7 vol%) achieves 98% Coulombic efficiency at 4.3V.

Case 2: Pharmaceutical Intermediates

Process: 15% yield increase in paliperidone synthesis using TEGDME vs. THF.

4. Client Case Studies

4.1 ABC Lithium Co., Ltd. (China)

Challenge: Electrolyte decomposition above 4.2V in NMC811 cells.
Solution: 20% TEGDME additive extended cycle life by 300 cycles at 4.4V.
Result: 15% reduction in pack cost for EV batteries.

4.2 PharmaCore Inc. (USA)

Challenge: Low solubility of steroid intermediates in polar solvents.
Solution: TEGDME-based reaction system at 80°C improved yield by 22%.
Result: FDA approval accelerated by 6 months.

5. Request a Quote

Optimize your processes with TEGDME tailored to your requirements:

Email: info@vivalr.com
Phone: (86) 15866781826

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