2-Adamantanone Cas 700-58-3

Chemical Name: 2-Adamantanone
CAS No.: 700-58-3
Molecular Fomula: C10H14O
Molecular weight: 150.22
Appearance: White crystalline solid
Assay: 99%min

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1. Product Specifications & Comparative Analysis

Parameter 2-Adamantanone (700-58-3) Alternative Derivatives
Molecular Formula C10H14O C10H16O (Adamantanol)
Molecular Weight 150.22 g/mol 152.23 g/mol
Melting Point 256-258°C (sublimation) 289-291°C
Boiling Point 246.7°C at 760 mmHg 315°C (estimated)
Density 1.105 g/cm³ 1.02 g/cm³
Purity ≥99% (HPLC) ≥97% (GC)

2. Functional Applications

Pharmaceutical Intermediates: Serves as precursor for neuroprotective agents and antiviral compounds due to its rigid adamantane structure.

Advanced Materials: Enhances thermal stability in polymer matrices for high-performance engineering plastics.

Photoresist Technology: Improves resolution in semiconductor lithography processes through controlled ketone reactivity.

Organic Synthesis: Facilitates asymmetric catalysis in chiral molecule construction.

3. Operational Guidelines

Handling Protocol:

  • Storage: Maintain at 2-8°C in sealed containers under inert gas
  • Solubility: 25 mg/mL in methanol (20°C)
  • Safety: Use NIOSH-certified respirators when handling powder form

Reaction Example:
Nucleophilic Addition: React with Grignard reagents (1:1 molar ratio) in THF at -78°C to produce tertiary alcohols.

4. Industry Case Studies

Case 1: Antiviral Drug Development
A Wuhan-based pharmaceutical company utilized 2-adamantanone (99.5% purity) to synthesize rimantadine analogs, achieving 92% yield in key amination steps.

Case 2: OLED Material Research
Shanghai Tech Institute reported 18% efficiency improvement in blue-emitting layers by incorporating 0.3% 2-adamantanone dopant.

Case 3: Industrial Catalyst Production
Solarbio (Beijing) developed palladium-based catalytic systems using 2-adamantanone ligands, demonstrating 150+ turnover cycles in cross-coupling reactions.

5. Commercial Inquiry

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Lead Time 3-5 business days for samples
15 days for bulk orders (25kg+)
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