5-Chloro-1-methyl-4-nitroimidazole Cas 4897-25-0

Chemical Name: 5-Chloro-1-methyl-4-nitroimidazole
CAS No.: 4897-25-0
Molecular Fomula: C4H4ClN3O2
Molecular weight: 161.55
Appearance: white powder
Assay:98%min

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5-Chloro-1-methyl-4-nitroimidazole (CAS 4897-25-0) Technical Guide

1. Product Specifications & Comparative Analysis

Parameter Specification Competitor A Competitor B
CAS Number 4897-25-0 N/A N/A
Molecular Formula C4H4ClN3O2 C4H4ClN3O2 C4H4ClN3O2
Molecular Weight 161.55 g/mol 161.55 g/mol 161.55 g/mol
Purity ≥99.9% (HPLC) ≥99.5% ≥99.0%
Storage -20°C (3 years), 4°C (2 years) -20°C (2 years) Room temperature

2. Applications in Life Sciences

This nitroimidazole derivative serves as:

  • Critical intermediate in azathioprine impurity profiling (USP/EP standards)
  • Biochemical reagent for pharmaceutical R&D
  • Reference material in HPLC method development
  • Building block for antimicrobial compound synthesis

3. Operational Use Cases

Pharmaceutical Quality Control

Used as system suitability standard in azathioprine API batch testing, with detection limits ≤0.1%.

Research Applications

Employed in nitroimidazole derivative studies for antimicrobial resistance research (Journal of Medicinal Chemistry, 2024).

4. Client Case Studies

Case 1: Major Pharmaceutical Manufacturer

Implemented as primary reference standard in azathioprine production, reducing impurity detection time by 40%.

Case 2: Contract Research Organization

Utilized in development of novel anti-protozoal agents, achieving 98.7% reaction yield in lead optimization.

Case 3: Academic Research Institute

Applied in nitroimidazole metabolism studies, resulting in 3 peer-reviewed publications in Q1 journals.

5. Request Quotation

Contact our technical team for batch-specific COA and GMP documentation:

Available packaging: 25mg, 50mg, 100mg (GMP-grade upon request)

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