4,7-dibroMo-5,6-dinitrobenzo[c][1,2,5]thiadiazole  Cas 76186-72-6

Chemical Name: 4,7-dibroMo-5,6-dinitrobenzo[c][1,2,5]thiadiazole
CAS No.: 76186-72-6
Molecular Fomula:C6Br2N4O4S
Molecular weight: 383.96
Appearance: yellow crystal
Assay:98%min

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4,7-Dibromo-5,6-dinitrobenzo[c][1,2,5]thiadiazole (CAS 76186-72-6) Comprehensive User Guide

1. Product Overview and Parameter Comparison

Key Specifications

Parameter Value
CAS Number 76186-72-6
Molecular Formula C₆HBr₂N₄O₄S
Molecular Weight 411.96 g/mol
Appearance Yellow crystalline powder
Purity ≥98% (HPLC)

Comparative Analysis

Feature 4,7-Dibromo Derivative Standard Benzo[c]thiadiazole
Electron Deficiency High (nitro/bromo groups) Moderate
Thermal Stability Up to 250°C 200°C
Solubility DMSO, DMF THF, Chloroform

2. Detailed Applications and Use Cases

Core Applications

  • Organic Electronics: Key building block for n-type semiconductors in OLED displays
  • Pharmaceutical Intermediates: Synthesis of kinase inhibitors in cancer research
  • Coordination Chemistry: Ligand precursor for transition metal complexes

Operational Workflow

Typical reaction protocol for Suzuki-Miyaura coupling:

  1. Charge 1.0 mmol of 4,7-dibromo-5,6-dinitrobenzo[c][1,2,5]thiadiazole in anhydrous DMF
  2. Add 2.2 mmol arylboronic acid under nitrogen atmosphere
  3. Catalyze with Pd(PPh₃)₄ (0.05 equiv) at 80°C for 12h
  4. Isolate product via column chromatography (Hexane:EA = 3:1)

3. Client Success Stories

Case Study 1: OLED Material Development

Client: Advanced Optoelectronics Co., Ltd. (Shenzhen, China)

Challenge: Required electron-transport material with LUMO ≤ -3.8 eV

Solution: Synthesized triazine derivatives using 76186-72-6 as core structure

Result: Achieved 18% external quantum efficiency in blue OLED devices

Case Study 2: Anticancer Drug Discovery

Client: Shanghai Medichem Research Institute

Challenge: Needed stable halogenated scaffold for PROTAC development

Solution: Utilized bromine sites for click chemistry functionalization

Result: Produced lead compound with 50 nM IC50 against BTK kinase

4. Technical Inquiry and Custom Solutions

Our technical team specializes in:

  • Bulk synthesis (up to 50kg batches)
  • Derivative customization (fluoro, iodo, or amino substitutions)
  • Analytical support (HPLC, NMR, MS characterization)

Contact our experts:
Email: info@vivalr.com
Phone: (86) 15866781826

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