Table of Contents
- Product Overview
- Technical Specifications & Comparison
- Industrial Applications
- Formulation Guidelines
- Client Success Stories
- Contact for Technical Support
Polyglyceryl-2 Oleate (CAS 49553-76-6) Technical Profile
Key Identifiers
| Parameter | Specification |
|---|---|
| Chemical Name | Polyglyceryl-2 oleate |
| CAS Number | 49553-76-6 |
| Molecular Formula | C21H40O6 |
| Appearance | Yellow to amber viscous liquid |
| Solubility | Dispersible in oils, soluble in ethanol |
| HLB Value | 6-8 (Oil-in-water emulsifier) |
| Melting Point | -10°C to 5°C |
| Storage | 2-8°C in airtight containers |
Performance Comparison
Grade Differentiation
| Parameter | Industrial Grade | Cosmetic Grade |
|---|---|---|
| Purity | >92% | >98% |
| Acid Value | ≤3 mg KOH/g | ≤1.5 mg KOH/g |
| Peroxide Value | ≤5 meq/kg | ≤2 meq/kg |
| Heavy Metals | <10 ppm | <5 ppm |
Functional Applications
Cosmetic Formulations
• Primary emulsifier in O/W systems (1-5% concentration)
• Texture modifier in anhydrous formulations
• Compatibility enhancer for silicone oils
Pharmaceutical Uses
• Transdermal drug delivery enhancer
• Topical ointment stabilizer
• Solubilizer for hydrophobic APIs
Industrial Applications
• Lubricant additive (0.5-2% load)
• Metalworking fluid component
• Polymer plasticizer
Formulation Protocol
Optimal Processing Parameters
| Application | Temperature Range | Mixing Speed |
|---|---|---|
| Emulsions | 65-75°C | 1500-3000 rpm |
| Anhydrous Systems | 40-50°C | 500-800 rpm |
Stability Considerations
• Maintain pH 5-7 for optimal performance
• Avoid prolonged exposure >80°C
• Conduct compatibility testing with ionic compounds
Client Implementation Cases
Case 1: Premium Skincare Emulsion
Client: European Cosmetic Manufacturer (Est. 1998)
Challenge: Phase separation in SPF 50 emulsion
Solution: 3% Polyglyceryl-2 oleate + 1% Glyceryl stearate
Result: 18-month stability at 40°C/75% RH
Case 2: Pharmaceutical Ointment
Client: Asian Pharma Company (Top 10 Generic Producer)
Challenge: Poor API release profile
Solution: 4% Polyglyceryl-2 oleate matrix
Result: 2.3x bioavailability improvement
Case 3: Industrial Lubricant
Client: US Machinery Producer (NASDAC Listed)
Challenge: High-temperature viscosity loss
Solution: 1.5% additive package
Result: 40% reduction in wear particles
Technical Consultation
Expert Support Services
• Custom formulation development
• Regulatory documentation support (REACH, COSMOS)
• Batch-specific technical data packages
Contact Our Chemists
Email: info@vivalr.com
Tel: (86) 15866781826
Office Hours: Mon-Fri 08:00-17:00 GMT+8
Frequently Asked Questions
Q1: Natural origin certification?
Available upon request (Ecocert/COSMOS standards)
Q2: Minimum order quantity?
Sample: 100g
Production: 25kg drum
Q3: Shelf life under different storage?
24 months @ 2-8°C
12 months @ 25°C



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